Publications by authors named "H Awan"

The construction industry significantly impacts the environment through natural resource depletion and energy consumption, leading to environmental degradation. Circular Economy (CE) material efficiency strategies-such as material reuse, design for disassembly, prefabrication, and recycling-offer promising solutions for reducing resource consumption and waste. This paper explores stakeholders' perspectives on the costs and benefits of implementing CE material efficiency strategies in the construction industry, using the 3-R (Reduce, Reuse, Recycle) framework.

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Background: RNA 5-methyluridine (m5U) modifications play a crucial role in biological processes, making their accurate identification a key focus in computational biology. This paper introduces Deep-m5U, a robust predictor designed to enhance the prediction of m5U modifications. The proposed method, named Deep-m5U, utilizes a hybrid pseudo-K-tuple nucleotide composition (PseKNC) for sequence formulation, a Shapley Additive exPlanations (SHAP) algorithm for discriminant feature selection, and a deep neural network (DNN) as the classifier.

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Background: People with long-term physical conditions are more likely to experience distress, depression or anxiety. Physical-mental comorbidity is associated with lower quality of life, poorer clinical outcomes, and increased mortality than physical conditions alone. South Asians (SAs) are the largest minority group in the UK, and more likely to have long-term conditions (LTCs) such as diabetes and heart disease.

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Article Synopsis
  • Researchers are investigating how artificial intelligence (AI) can help measure functional small airways disease (fSAD) in chronic obstructive pulmonary disease (COPD) using just one CT scan instead of the two traditionally required.
  • They studied over 2,500 participants and found strong correlations between the new AI method and existing measures of lung function, confirming its effectiveness.
  • The new AI technique for estimating fSAD proved to be more reliable and repeatable compared to standard methods, suggesting it could enhance clinical assessments of COPD.
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Article Synopsis
  • RNA modifications are crucial for cellular regulation, influencing gene expression and protein function, particularly through processes like cytosine hydroxymethylation driven by the TET enzyme.
  • Traditional methods for identifying 5-hydroxymethylcytosine (5hmC) are costly and inefficient, prompting the introduction of XGB5hmC, a machine learning algorithm that utilizes XGBoost and enhanced residue-based features for better identification.
  • The XGBoost model showed impressive performance metrics, achieving nearly 90% accuracy and improving interpretability through SHAP-based feature selection, indicating a significant advancement in RNA modification analysis that could benefit medical assessments and treatments.
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