Publications by authors named "H Askari"
Improvement of RBD-FC Immunogenicity by Using Alum-Sodium Alginate Adjuvant Against SARS-COV-2.
Influenza Other Respir Viruses
November 2024
Background: Adjuvants use several mechanisms to boost immunogenicity and to modulate immune response. The strength of adsorption of antigen by adjuvants can be a determinant factor for significant improvement of immunopotentiation.
Methods: We expressed recombinant RBD-FC in PichiaPink Strain 4 and examined the vaccination of mice by vaccine formulation with different adjuvants (sodium alginate and aluminum hydroxide, alone and together).
Article Synopsis
- - Dust leads to several issues including environmental and health risks, but microorganisms can enhance soil properties to counteract these problems.
- - A study explored 60 bacterial strains from arid soils for their ability to precipitate calcium carbonate, with several strains identified as effective, mainly from the Bacillus and Pseudomonas genera.
- - The B. subtilis strain S56 was found to be particularly promising, producing high yields of calcite crystals, making it a candidate for reducing soil erosion and dust pollution in harsh environments.
Article Synopsis
- * A total of 13 quantitative trait loci (QTLs) were identified across five rice chromosomes, with 11 of them explaining significant phenotypic variation in tocopherol levels.
- * The research highlights genes and proteins potentially regulating tocopherol contents, providing valuable information for breeding and biofortification strategies aimed at enhancing antioxidant levels in rice and other cereals.
Article Synopsis
- Stroke is a serious neurological disorder, with ischemic strokes making up about 80% of cases, and the main treatments are thrombolysis and thrombectomy, which don’t always lead to full recovery for patients.
- There is growing interest in stem cell therapy, particularly using induced pluripotent stem cells (iPSCs), for promoting brain repair and regeneration, but challenges like tumor formation and immune rejection complicate their use.
- The study also explores cell-free therapies like exosomes and microvesicles as promising alternatives to iPSC treatment, aiming to address the limitations faced by direct stem cell therapies.
Article Synopsis
- The study shows that having too much visceral fat (VAT) is linked to heart disease and diabetes, while having more subcutaneous fat (SAT) might not be as bad if VAT is not high.
- Scientists fed mice a high-fat diet to see how obesity affects specific fat types and found that obesity changes the way fat genes work.
- They discovered that certain genes behave differently in SAT and VAT when mice are obese, and these genes could help us understand more about fat and health problems.