In the study of coronary artery disease, the mechanisms underlying atherosclerosis initiation and progression or regression remain incompletely understood. Our research conceptualized the cardiovascular system as an integrated network of pumps and pipes, advocating for a paradigm shift from static imaging of coronary stenosis to dynamic assessments of coronary flow. Further review of fluid mechanics highlighted the water hammer phenomenon as a compelling analog for processes in coronary arteries.
View Article and Find Full Text PDFBacterial elicitors are recognized for their ecological role in stimulating plant defenses and enhancing the production of beneficial metabolites. This study explores the antibiotic potential of endophytic Bacillus velezensis VTRNT 01, isolated from Adenosma bracteosum Bonati, under co-cultivation with bacterial elicitors (Staphylococcus aureus, Escherichia coli, and Aeromonas hydrophila). By leveraging these interactions, we aim to unlock the full potential of endophytic bacteria for sustainable applications in agriculture and pharmaceuticals.
View Article and Find Full Text PDFWe report the discovery and characterization of bacteriophages ASegato, DejaVu, Judebell, and RicoCaldo, isolated from grass samples collected in Quincy, Massachusetts, using B-24224 as the isolation host. Based on gene content similarity, these phages are assigned to actinobacteriophage clusters ED2, ED1, EG, and EK2 respectively.
View Article and Find Full Text PDFBackground: New-onset arrhythmias are common in patients with chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA). However, scarce data exists regarding arrhythmia risk in overlap syndrome (OS), encompassing COPD and OSA.
Objective: We compared the incidence of new onset atrial and ventricular arrhythmias in patients with COPD, OSA, and OS.
In this study, berberine nanoparticles (BerNPs) were prepared using a wet-milling method with zirconium balls to enhance bioavailability and expand potential applications. The particle size and physicochemical properties of the BerNPs were analyzed using field-emission scanning electron microscopy (FE-SEM), UV-vis spectroscopy, X-ray diffraction, and Fourier-transform infrared spectroscopy. The broth dilution method was used to determine the antimicrobial activity of the BerNPs against ().
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