Publications by authors named "H Akin"
More than three billion years of evolution have produced an image of biology encoded into the space of natural proteins. Here we show that language models trained at scale on evolutionary data can generate functional proteins that are far away from known proteins. We present ESM3, a frontier multimodal generative language model that reasons over the sequence, structure, and function of proteins.
View Article and Find Full Text PDFPurpose: This study was conducted as a randomized controlled trial to examine the effect of toys made from medical materials on anxiety among hospitalized children.
Design And Methods: This study was conducted with pediatric patients aged 4-6 years who were hospitalized in the pediatrics department of a teaching and research hospital in the Southeastern Anatolia Region. The study was completed with 90 children, allocated to the toys made of medical materials group (45) and the control group (45).
Can Laryngeal Mask Airway be the First Choice for Tracheal Stenosis Surgery? A Historical Cohort Study.
Sisli Etfal Hastan Tip Bul
September 2024
Objectives: To compare the usage of laryngeal mask airway (LMA) and orotracheal intubation (OTI), which are separate airway management methods in tracheal reconstruction surgeries, in terms of perioperative management, mortality, and morbidity.
Methods: Adult patients who underwent tracheal reconstruction surgery between June 2020 and June 2022 were included in the study, retrospectively. Patients with lost data or primary tracheal malignancy were excluded.
Article Synopsis
- The study focuses on a case involving a 49-year-old woman diagnosed with rheumatoid arthritis and subsequent severe immune deficiency due to a homozygous mutation in the LRBA gene, which is crucial for immune regulation.
- The patient showed various symptoms, including massive splenomegaly, portal hypertension, and a rare type of cystitis associated with mast cells, indicating a complex clinical presentation.
- This case emphasizes the importance of understanding LRBA's role in immune function and the diverse clinical manifestations linked to its deficiency.
How Does the Anxiety of Primiparae Affect Their Readiness for Newborn Care? Ethnic Primiparous Experiences.
J Racial Ethn Health Disparities
September 2024
Background: The study was conducted to investigate the relationship between pregnancy-related anxiety levels of primiparae living in an ethnic region and their readiness for postnatal hygienic care of newborns.
Method: The study conducted between February and May 2023 included 201 "18-40-year-old primiparae" who lived in an ethnic region and volunteered to participate in the study. The population of the study consisted of all pregnant women who presented to the Gynecology and Obstetrics Clinic, Pregnancy Outpatient Clinic of a city hospital.