Publications by authors named "H Akabane"

Gastrointestinal stromal tumors surrounding the esophagogastric junction are often challenging to resect, with no consensus regarding the optimal surgical technique. Here in, we present a case of concurrent gastric cancer in the antrum and gastrointestinal stromal tumors adjacent to the esophagogastric junction. The patient underwent simultaneous distal gastrectomy and local resection assisted by a surgical robot, avoiding the need for total gastrectomy.

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Therapy with an aromatase inhibitor(AI)was initiated in a 91-year-old female patient after she had been diagnosed with breast cancer. One week after taking the medicine, she experienced multiple joint pain in her upper extremities. Finally, she was diagnosed with rheumatoid arthritis(RA).

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In the last decade, advancements in understanding the genetic and molecular mechanisms of acute myeloid leukemia (AML) have significantly improved treatment options. Techniques such as immunophenotyping, cytogenetics, and next-generation sequence (NGS) testing are now standard practices for patient assessments, allowing for personalized therapies based on individual patient needs. Our study aimed to evaluate the impact of cytogenetics and NGS on initial treatment decisions for AML at our institution.

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Article Synopsis
  • The FDA has approved TNF alpha inhibitors for treating various inflammatory conditions, but there is a potential risk for secondary blood cancers due to their effects on cell processes.
  • The article details a specific case of a patient who developed Philadelphia-positive acute lymphoblastic leukaemia while on adalimumab, a TNF-alpha blocker.
  • The patient was treated successfully with chemotherapy and tyrosine kinase inhibitors, leading to complete remission, and the authors found five other similar cases in their literature review.
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Castleman disease (CD) is a rare lymphoproliferative disease. Hyaline-vascular type unicentric CD has a good prognosis if completely resected during surgery. However, follicular dendritic cell proliferative lesions have the potential for recurrence and metastasis.

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