Publications by authors named "H Adamson"

Article Synopsis
  • Researchers have observed that the effectiveness of therapeutic monoclonal antibodies (TmAb) can greatly depend on their concentration in the bloodstream, where low levels can be ineffective and high levels can cause side effects.
  • Current therapeutic drug monitoring (TDM) methods for these treatments are slow and centralized, highlighting the need for quicker, more personalized approaches.
  • The study introduces four point-of-care (PoC) biosensors that use advanced technology to rapidly measure TmAb levels in under 10 minutes, potentially improving treatment outcomes for patients undergoing immunotherapy.
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Adult second language (L2) learning is a challenging enterprise inducing neuroplastic changes in the human brain. However, it remains unclear how the structural language connectome and its subnetworks change during adult L2 learning. The current study investigated longitudinal changes in white matter (WM) language networks in each hemisphere, as well as their interconnection, in a large group of Arabic-speaking adults who learned German intensively for 6 mo.

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Introduction: Communication is an essential skill for all healthcare professionals but is particularly challenging for diagnostic radiographers since their role involves conveying extensive information within a relatively short amount of time. One method to develop communication skills in radiography is through simulation-based training using high fidelity simulation activities. The use of video recording for reflection and debriefing are also important elements that can be utilised to enhance learning.

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Article Synopsis
  • Therapeutic monoclonal antibodies (TmAb) are effective treatments for cancers and autoimmune diseases, but their effectiveness can vary greatly between patients, making therapeutic drug monitoring (TDM) important for dosage optimization.
  • This study presents a novel enzyme switch sensor platform, combining β-lactamase with custom binding proteins, to rapidly and sensitively measure the levels of two specific TmAbs, trastuzumab and ipilimumab, in blood serum.
  • While the sensor successfully detected these two antibodies at low concentrations suitable for therapy, it struggled with other antibodies, highlighting its potential for bedside monitoring and personalized treatment adjustments.
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