Serum and Urinary Orosomucoid in Young Patients With Type 1 Diabetes: A Link Between Inflammation, Microvascular Complications, and Subclinical Atherosclerosis.

Orosomucoid is an acute-phase serum protein that is upregulated in urine samples of patients with diabetic nephropathy. We assessed serum and urinary orosomucoid levels in children and adolescents with type 1 diabetes and their relation to microvascular complications and carotid intima-media thickness (CIMT). Sixty patients with type 1 diabetes were divided into 2 groups according to the presence of microvascular complications and compared with 60 healthy controls.

[Esthetic pinching of the globular nasal tip. Technical note].

A conservative technique designed to simple reduce the width of nasal tip is presented. It consists of approximation of the anterosuperior segments of alar lateral crus after their elevation on median pedicles. A marginal inferior band of alar cartilage is left adherent to the nasal mucosa.