Publications by authors named "H A Ogwoni"
Article Synopsis
- - This study explores the impact of Bisphenol A (BPA), an endocrine disruptor known to affect male fertility, on the testicular mitochondria of male albino rats and tests the protective effects of seed oil (CMSO).
- - Six groups of rats were used, with varying doses of BPA and CMSO; the study measured mitochondrial enzyme activity, membrane potential, protein levels, and body weight post-exposure.
- - Results showed that BPA reduced key mitochondrial activities and rat body weight, but coadministration of CMSO helped restore these disrupted functions, suggesting CMSO could be a potential treatment for toxins like BPA.
This study demonstrated the therapeutic potentials of seed oil (CMSO) capable of alleviating BPA-induced dyslipidemia and adipokine dysfunction. In this study, we evaluated the effects of CMSO on adipokine dysfunctions and dyslipidemia in bisphenol-A (BPA)-induced male Wistar rats. Six-week-old 36 albino rats of 100-200 g weight were assigned randomly to six groups, which received varied doses of BPA and/or CMSO.
View Article and Find Full Text PDFThere has been increasing search for the ameliorative properties of seed oils against toxicants. bisphenol A acts as an estrogenic endocrine-disrupting chemical capable of causing male infertility. This study aimed to explore seed oil effects against mitochondrial damage in rats using bisphenol A.
View Article and Find Full Text PDFBackground: Male reproductive health has deteriorated in recent years as a result of industrialization, which has led to the use of desirable chemicals, like Bisphenol A (BPA), of underlying toxicity. seed is a common soup thickener that produces vegetable oil as well as essential nutrients making it a source of nutraceuticals enlisted with a wide range of therapeutic effects.
Methods: A total of 48 adult male Wistar rats (120 ± 200g) were used in this study.