Drug Development.

Background: Donepezil, an acetylcholinesterase inhibitor (AChEI), is an FDA-approved drug to treat these neurodegenerative diseases, e.g., Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI).

Biodegradation of azo dyes by Aspergillus flavus and its bioremediation potential using seed germination efficiency.

The worldwide textile industry extensively uses azo dyes, which pose serious health and environmental risks. Effective cleanup is necessary but challenging. Developing bioremediation methods for textile effluents will improve color removal efficiency.

Revitalizing Soybean Plants in Saline, Cd-Polluted Soil Using Si-NPs, Biochar, and PGPR.

Excessive irrigation of saline-alkaline soils with Cd-contaminated wastewater has resulted in deterioration of both soil and plant quality. To an investigate this, a study was conducted to explore the effects of biochar (applied at 10 t ha), PGPRs ( (USDA 110) + at 1:1 ratio), and Si-NPs (25 mg L) on soybean plants grown in saline-alkali soil irrigated with wastewater. The results showed that the trio-combination of biochar with PGPRs, (as soil amendments) and Si-NPs (as foliar spraying), was more effective than individual or coupled applications in reducing Cd bioavailability in the soil, minimizing its absorption, translocation and bioconcentration in soybean tissues.

The Moderating Role of Emotional Intelligence on the Relationship Between Nurses' Preparedness to Care for COVID-19 Patients and Their Quality of Work Life.

Emotional intelligence (EI) is increasingly recognized as a key factor in healthcare, where managing emotions is vital for job satisfaction, productivity, and interpersonal relationships. For nurses, particularly during the COVID-19 pandemic, EI plays a pivotal role in navigating emotional challenges and improving their quality of work life (QoWL). This study examined how EI moderates the relationship between nurses' preparedness to care for COVID-19 patients and their QoWL.

Synthesis of Schiff bases based on Chitosan, thermal stability and evaluation of antimicrobial and antitumor activities.

A Schiff base of Chitosan was prepared by condensing of the Chitosan (CS) with six aromatic aldehydes and confirmed by FT-IR, NMR, XRD, TGA, and DSC. XRD results showed the disappeared of peaks at 2θ = 10° for CS and appeared one peaks at around 2θ of 23° for Schiff bases, while TGA was demonstrated that the thermal stability of CS has improved after the modification with the corresponding aldehyde. Also, DSC shows endothermal peak of CS at 100 °C due to the loss of water and second thermal event related to the decomposition of amine units with an exothermic peak at 295 °C, while Schiff bases shows endothermal peak around 70-95 °C which is related to the loss of water for all samples and the second exothermic peak around 260-280 °C is related to the decomposition of the amine group in the polymer units.