Publications by authors named "H A Lacey"
Emerging Therapeutic Modalities and Pharmacotherapies in Neuropathic Pain Management: A Systematic Review and Meta-Analysis of Parallel Randomized Controlled Trials.
Pain Res Manag
January 2025
Neuropathic pain (NP) is a chronic condition caused by abnormal neuronal excitability in the nervous system. Current treatments for NP are often ineffective or poorly tolerated. Hence, we reviewed the efficacy and safety of novel drugs or devices that target neuronal excitability in NP patients compared with placebo, sham, or usual care interventions.
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- The British Orthopaedic Association Standards for Trauma and Orthopaedics (BOAST) provide guidelines for treating open lower limb fractures, and an audit was conducted to evaluate the adherence to these standards in a Southeast England trauma center.
- The audit analyzed data from 133 patients from August 2020 to August 2022, revealing that most patients were older women who sustained fractures from low-energy injuries, with a significant number undergoing timely debridement and closure procedures.
- While the management of these fractures generally aligned with BOAST guidelines, improvements are needed in initial debridement practices, emphasizing the importance of training and resource allocation to enhance compliance.
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- A rare case of short-segment jejunal infarction occurred after an inferior mesenteric artery embolization in a patient with a history of endovascular abdominal aortic aneurysm repair.
- Potential explanations for the infarction include thromboembolism or injury to a branch of the superior mesenteric artery due to the use of a guide wire during the procedure.
- The condition was diagnosed via CT scan and managed by surgical resection of the affected bowel segment, followed by primary anastomosis to reconnect the intestines.
Background: Merkel cell carcinoma (MCC) is a rare cutaneous malignancy with high metastatic potential. Sentinel lymph node biopsy (SLNB) is used to assess locoregional spread, facilitate staging, and inform prognosis. Positive nodal status is associated with higher recurrence rates and reduced overall survival.
View Article and Find Full Text PDFTwo decades have elapsed since our publication of 'What kind of illness is anorexia nervosa?'. The question remains whether our understanding of anorexia nervosa and its treatment thereof has evolved over this time. The verdict is disappointing at best.
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