Publications by authors named "H A Jennings"

Background: There is a lack of evidence on effective treatments for depression in people with T2DM, particularly in Low and Middle-Income Countries (LMICs). This study aims to test the feasibility and acceptability of a culturally adapted Behavioural Activation (BA) intervention (DiaDeM) for people with depression and T2DM in two South Asian LMICs.

Methods: A multicountry, individually randomised-controlled feasibility trial was conducted from March 2022 to November 2022.

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Article Synopsis
  • The World Health Organization (WHO) promotes evidence-based interventions, known as "Best Buys," to tackle non-communicable diseases (NCDs), but there is limited knowledge about their implementation in sub-Saharan Africa, particularly in Ghana.
  • This study used a mixed-methods approach, combining document reviews of Ghana's WHO Best Buys scores from various years and interviews with key policymakers to assess how well these NCD policies are being implemented and identify any gaps.
  • Findings indicate that while Ghana shows some progress in adopting WHO Best Buys, with fluctuating implementation scores, significant challenges persist, including socio-cultural issues, stakeholder engagement, policy enforcement, and limited public awareness and financing for NCD prevention.
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We investigated the effectiveness of interventions provided by traditional healers for common mental disorders (CMDs) together with associated barriers and facilitators. Electronic databases including MEDLINE, APA Psych Info, Allied and Complementary Medicine, Embase, CINAHL, Social Science Citation Index, and Scopus were searched from inception until October 2021. Randomised controlled trials (RCTs) assessing interventions by traditional healers for CMDs and qualitative and mixed-methods studies examining traditional healers and their attendees' views about the treatment of CMDs by traditional healers were included.

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Background: Non-communicable diseases (NCDs) predispose households to exorbitant healthcare expenditures in health systems where there is no access to effective financial protection for healthcare. This study assessed the economic burden associated with the rising burden of type-2 diabetes (T2D) and hypertension comorbidity management, and its implications for healthcare seeking in urban Accra.

Methods: A convergent parallel mixed-methods study design was used.

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Background: Normothermic ex vivo liver perfusion (NEVLP) is an exciting strategy to preserve livers prior to transplant, however, the effects of NEVLP on the phenotype of tissue-resident immune cells is largely unknown. The presence of tissue-resident memory T cells (TRM) in the liver may protect against acute rejection and decrease allograft dysfunction. Therefore, we investigated the effects of NEVLP on liver TRMs and assessed the ability of anti-inflammatory cytokines to reduce TRM activation during NEVLP.

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