Health impacts of health system implementation of a food-as-medicine strategy.

Objectives: To describe a regional health system's experience with medically tailored groceries (MTG), focusing on program reach and effectiveness as determined by observed within-person changes in cardiometabolic measures.

Study Design: Case study including individuals aged 18 to 79 years referred by an ambulatory health care provider to a single regional health system's MTG program from April 2020 through September 2023.

Methods: Demographics, clinical characteristics, and cardiometabolic measures (blood pressure [BP], weight, body mass index [BMI], and hemoglobin A1c [HbA1c]) were abstracted from electronic health records.

ROR2 drives right ventricular heart failure via disruption of proteostasis.

Background: No therapies exist to reverse right ventricular failure (RVF), and the molecular mechanisms that drive RVF remain poorly studied. We recently reported that the developmentally restricted noncanonical WNT receptor ROR2 is upregulated in human RVF in proportion to severity of disease. Here we test mechanistic role of ROR2 in RVF pathogenesis.

Limited evidence to support demineralized bone matrix in foot and ankle surgical procedures: A systematic review.

Background: Demineralized bone matrix (DBM) is a commonly utilized allogenic bone graft substitute to promote osseous union. However, little is known regarding outcomes following DBM utilization in foot and ankle surgical procedures.

Aim: To evaluate the clinical and radiographic outcomes following DBM as a biological adjunct in foot and ankle surgical procedures.

Recent and future trends in osteopathic orthopedic surgery residency match rates following the transition to a single accreditation system.

Context: Medical education in the United States has undergone significant changes, specifically within the osteopathic community. In 2020, a merger occurred between the American Osteopathic Association (AOA) and the Accreditation Council for Graduate Medical Education (ACGME), forming a single accreditation system (SAS) for graduate medical education and residency placement, with the purpose to create consistency within graduate medical education and to provide equal opportunities for applicants pursuing all specialties in medicine. However, osteopathic medical students, especially students applying to competitive residencies including orthopedic surgery, have faced challenges, raising concerns about future implications within this field.

Treating shock with norepinephrine administered in midline catheters in an intermediary care unit: a retrospective cohort study.

Objectives: A rising incidence of septic shock as well as recommendations for early vasopressor initiation has increased the number of patients eligible for norepinephrine (NE). Traditionally, NE has been administered through central lines, in intensive care units, due to the risk of extravasation in peripheral lines. The aim of the current study is to determine the rate of complications and patient outcomes when NE is administered through midline catheters (MCs) in intermediary care units (IMCUs).