Autonomic functions, tinnitus annoyance and loudness, and quality of life: Randomized-controlled responses to bee-humming (vibrational) respiratory training in tinnitus elderly.

Background: In chronic subjective tinnitus (CST) studies, the effect of bee-humming respiratory training (BHRT), a type of pranayama breathing technique, on autonomic cardiovascular/respiratory physiological functions (systolic pressure, rates of breathing and pulse, and diastolic pressure), tinnitus annoyance (TA), tinnitus loudness (TL), and quality of life measures as tinnitus handicap inventory (THI) did not receive significant attention.

Objective: This study aimed to investigate the efficacy of BHRT on TL, THI, TA, and cardiovascular/respiratory autonomic functions in bilateral CST elderly (aged ≥65 years old).

The Design, Setting, Participants, And Intervention: The current study employs a prospective, single-blind design; it is a randomized-controlled for-tinnitus behavioral intervention.

Exploration of novel phthalazinone derivatives as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel.

Chemotherapy is an important means of cancer treatment. However, overexpression of efflux transporters (including but not limited to P-gp and BCRP) can lead to resistance to cancer chemotherapy. Multiple-target inhibitors of efflux transporter can be overcome the resistance and improve the oral bioavailability of chemotherapy drugs.

Agenesis of vermiform appendix; a case report with literature review.

Introduction: Agenesis of the vermiform appendix (AVA) is a very rare finding. The report aims to present a case of suspected acute appendicitis who lacked vermiform appendix during surgical exploration.

Case Presentation: A 25-year-old pregnant lady was presented with abdominal pain for a period of 2 days.

Estimation and Comparison of the Duration of the Pubertal Peak in Skeletal Class II and Class I Subjects Using the Cervical Vertebrae Maturation Index Method.

Aim: The purpose of this study is to estimate and compare the duration of the pubertal peak in skeletal class II and class I subjects and to detect any difference between boys and girls or between hypo-, normo-, and hyperdivergent subjects for skeletal maturation indicator (CVM) in white Caucasians.

Materials And Methods: 346 subjects were selected from 3,119 examined files. Pretreatment lateral cephalometric records were hand-traced and divided following the anteroposterior skeletal relationship, the gender, the vertical pattern, and the skeletal maturation.