Publications by authors named "H A Flynn"
Tractional Retinoschisis in Proliferative Diabetic Retinopathy Imaged With Swept-Source Optical Coherence Tomography Angiography.
Ophthalmic Surg Lasers Imaging Retina
January 2025
Tractional retinoschisis (TRS) secondary to proliferative diabetic retinopathy (PDR) may be differentiated from tractional retinal detachment (TRD) by its characteristically nonprogressive course. The purpose of the current study was to describe the use of swept-source optical coherence tomography angiography (SS-OCTA) in the diagnosis and monitoring of TRS secondary to PDR. Retrospective, consecutive case series of patients with TRS secondary to PDR are featured.
View Article and Find Full Text PDFIntroduction: Fungal keratitis is a leading cause of corneal blindness, with current antifungal treatments having limited efficacy. One promising treatment modality is Rose Bengal (RB) photodynamic antimicrobial therapy (PDAT) that has shown mixed success against fungal keratitis. Therefore, there is a need to explore the antimicrobial efficacy of other green-light activated photosensitizers that have deep penetration in the cornea to combat the deep fungal infections, such as Erythrosin B (EB) and Eosin Y (EY).
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of the protein phosphatase PP7 in the asexual blood stage development of malaria parasites, revealing that its disruption leads to severe growth arrest.
- PP7 is identified as a calcium-dependent phosphatase that interacts with calmodulin and calcium-dependent protein kinase 1 (CDPK1), indicating its involvement in calcium signaling essential for the parasite's development.
- The findings emphasize that while PP7 is not necessary for invading red blood cells, it is crucial for the ring-stage development, highlighting its importance in the life cycle of malaria parasites and the potential for targeting the protein for new drug discoveries.