The Transient Receptor Potential superfamily of proteins (TRPs) form cation channels that are abundant in animal sensory systems. Amongst TRPs, the Melastatin-related subfamily (TRPMs) is composed of members that respond to temperature, pH, sex hormones, and various other stimuli. Some TRPMs exhibit enriched expression in gonads of vertebrate and invertebrate species, but their contributions to germline development remain to be determined.
View Article and Find Full Text PDFPlants People Planet
September 2024
J Interdiscip Hist
April 2024
The organization of sweet potato research across global regions began in earnest in the 1980s. Leading international institutions, notably CGIAR (Consultative Group on International Agricultural Research) recognized the potential for science-driven development of a "neglected" crop. Sweet potato was second only to potato in root crop cultivation worldwide and the top tuber in Asia yet had not been subject to the internationally coordinated research that its importance merited.
View Article and Find Full Text PDFAdaptive radiotherapy (ART) was introduced in the late 1990s to improve the accuracy and efficiency of therapy and minimize radiation-induced toxicities. ART combines multiple tools for imaging, assessing the need for adaptation, treatment planning, quality assurance, and has been utilized to monitor inter- or intra-fraction anatomical variations of the target and organs-at-risk (OARs). Ethos™ (Varian Medical Systems, Palo Alto, CA), a cone beam computed tomography (CBCT) based radiotherapy treatment system that uses artificial intelligence (AI) and machine learning to perform ART, was introduced in 2020.
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