Excess retinoid acts through the stroma to produce mucous glands from newborn hamster cheek pouch in vitro.

Many morphogenetic processes are modified or initiated by retinoids. The cheek pouch of the newborn hamster can be induced to develop mucous glands in vitro by adding excess retinoid. The objective of this study was to determine whether the retinoid acted through the epithelium or the mesenchymal stroma.

Stability of the glandular morphogenesis produced by retinoids in the newborn hamster cheek pouch in vitro.

Retinoids can induce alterations in differentiation and morphogenesis in the hamster cheek pouch. In order to determine the stability of these changes, explants of neonatal pouch were exposed to 6 micrograms/ml of either retinyl acetate (RAc: 1.8 x 10(-5) M) or all-trans retinoic acid (RA: 2.

The development of the Syrian hamster cheek pouch.

The objective of this study was to provide a detailed account of the morphogenesis and early cytodifferentiation of the hamster cheek pouch. Although the newborn "cheek pouch" is used for in vitro studies of the effects of retinoids and carcinogens, its rudimentary structure has not been adequately described. Complete paraffin serial sections of the heads of 14- and 15-day fetuses were cut in three planes to determine the location and shape of the earliest pouch rudiments.