Publications by authors named "H A Brodie"
Deficits in cost/benefit decision making is a critical risk factor for gambling disorder. Reward-paired cues may play an important role, as these stimuli can enhance risk preference in rats. Despite extensive research implicating the dorsal striatum in the compulsive aspects of addiction, the role of nigrostriatal dopaminergic activity in cue-induced risk preference remains unclear, particularly in females.
View Article and Find Full Text PDFObjectives: There is a limited understanding of the impact of cochlear implantation (CI) in patients with Charcot-Marie-Tooth disease (CMT), given the scarcity of reported cases. We aim to evaluate the audiological outcomes and quality of life (QoL) after CI in CMT.
Methods: Multi-institutional, university-affiliated, tertiary-referral centers, retrospective chart review.
Purpose: This scoping review identifies and characterises reported barriers and facilitators to providing integrated cancer care reported in the international literature, and develops recommendations for clinical practice.
Methods: This scoping review included literature published between 2009 and 2022 and describes the delivery of integrated cancer care between primary and secondary care sectors. Searches were conducted of an online database Ovid Medline and grey literature.
Impulse control and/or gambling disorders can be triggered by dopamine agonist therapies used to treat Parkinson's disease, but the cognitive and neurobiological mechanisms underlying these adverse effects are unknown. Recent data show that adding win-paired sound and light cues to the rat gambling task (rGT) potentiates risky decision-making and impulsivity via the dopamine system, and that changing dopaminergic tone has a greater influence on behavior while subjects are learning task contingencies. Dopamine agonist therapy may therefore be potentiating risk-taking by amplifying the behavioral impact of gambling-related cues on novel behavior.
View Article and Find Full Text PDFArticle Synopsis
- A stratified approach to cancer follow-up care, including remote monitoring and self-management, is becoming more recommended, with patient portals being a key tool for access to health information.
- In a study evaluating a patient portal for men with prostate cancer, 60% registered, but only 37% logged in at least once in 6 months, indicating room for improvement in user engagement.
- While most users found the portal helpful and easy to use, 40% didn't use it due to factors like limited computer access and skills, highlighting the need to address these barriers to enhance care equity.