Publications by authors named "Gyoung-Deuck Kim"
Article Synopsis
- * In experiments with rats, HemoHIM G showed no signs of acute toxicity even at high doses (up to 5000 mg/kg/day) and did not lead to any adverse effects after 13 weeks of repeated dosing.
- * Tests conducted for potential genotoxicity confirmed that HemoHIM G is non-mutagenic and non-clastogenic, indicating it is safe for use as a food ingredient.
β-Thujaplicin, a natural monoterpenoid, has been demonstrated to exert health beneficial activities in chronic diseases. However, it has not been studied in regulating estrogen receptor (ER) negative breast cancer. Here, we investigated the effect of β-thujaplicin on inhibiting ER-negative basal-like breast cancer and the underlying mechanism of action using an in vitro and in vivo xenograft animal model.
View Article and Find Full Text PDFThe metabolomic screening of potential anti-inflammatory compounds in the leaves of was performed by using LC-MS/MS. Ethanol extracts were prepared, and the anti-inflammatory effects were investigated based on nitric oxide (NO) synthesis and inducible nitric oxide synthase expression in lipopolysaccharide-induced RAW 264.7 macrophages.
View Article and Find Full Text PDFBackground/objectives: leaves have been used in traditional medicine to treat bleeding, gastritis, hemorrhoids, and halitosis. However, their mechanisms have not been elucidated.
Materials/methods: The present study prepared two leaf extracts (NLEs) using water or 50% ethanol.