Car accident leading to "traumatic" macular hole formation proven by optical coherence tomography.

Background: We present the case of a car accident where the cause-consequence of the subsequent visual loss in one eye of the victim was proven by optical coherence tomography (OCT).

Methods: A 66-year-old woman was hit by a car from her right side and complained of immediate visual loss after the accident in her right eye. The patient was referred to our outpatient clinic 2.

Cataract surgery anaesthesia: is topical anaesthesia really better than retrobulbar?

Purpose: To compare the effectiveness for the patient of retrobulbar anaesthesia (RBA) and topical anaesthesia (TA) in cataract surgery by phacoemulsification.

Methods: We performed a prospective, randomized study on 115 patients operated at our clinic using the two anaesthesia techniques. The RBA group comprised 57 patients (20 women, 37 men; age 72 +/- 10 years); the TA group comprised 58 patients (20 women, 38 men; age 74 +/- 10 years).

Intraocular lens power calculation for combined cataract surgery, vitrectomy and peeling of epiretinal membranes for macular oedema.

Purpose: This study aimed to compare preoperatively calculated and postoperatively achieved refraction following phacoemulsification and intraocular lens (IOL) implantation combined with pars plana vitrectomy with internal limiting membrane or epiretinal membrane removal.

Methods: Twelve eyes of 12 patients who underwent a combined procedure were enrolled in this study. Ultrasound axial length and macular thickness (optical coherence tomography, OCT) measurements were performed pre- and postoperatively.

Functional assessment of the possible toxicity of indocyanine green dye in macular hole surgery.

Purpose: To evaluate the possible toxicity of indocyanine green (ICG) dye in macular hole surgery by comparing functional results after successful surgeries performed with and without staining.

Design: Prospective observational case series.

Methods: In a study conducted at our department, 30 eyes of 29 patients with idiopathic macular hole underwent pars plana vitrectomy, with peeling of the internal limiting membrane (ILM).

[Role of the music in the operating theatre].

Purpose: To investigate the effect of music on patients, surgeons and staff in the operating theatre at our Ophthalmology department in Mária street Clinic.

Patients And Methods: I. 150 patients, 7 staff and 19 surgeons have been asked to fill out a questionnaire.

Soluble semicarbazide-sensitive amine oxidase (SSAO) activity is related to oxidative stress and subchronic inflammation in streptozotocin-induced diabetic rats.

Diabetes is known to increase the risk of Alzheimer's disease (AD) and vascular dementia via oxidative stress and inflammation. There are speculations that SSAO activity might be related to the development of AD. Our aim was to investigate whether changes of soluble SSAO activity, oxidative stress and inflammation markers are related to each other in diabetes.

Correlation of clinical and genetic findings in Hungarian patients with Stargardt disease.

Purpose: Autosomal recessive Stargardt disease (arSTGD) presents with substantial clinical and genetic heterogeneity. This study was conducted to correlate foveolar thickness (FT) and total macular volume (TMV), measured by optical coherence tomography (OCT), with other clinical characteristics and with specific genetic variation in Hungarian patients with arSTGD.

Methods: After a standard ophthalmic workup, both eyes of 35 patients with STGD from Hungary and of 25 age-matched healthy control subjects were tested with OCT.

[Optical biopsy of the retina in vivo: on optical coherence tomography and its clinical use in ophthalmology].

Optical Coherence Tomography (OCT) is a novel, non invasive imaging method, which enables in vivo assessment of living tissues, providing near histological resolution images. The first description of its clinical introduction was in ophthalmology, which substantially changed our view of specific retinal diseases. OCT technology is slowly penetrating into other medical fields, supposedly opening new perspectives with the possibility of in vivo optical biopsy.

Laser treatment of zone I prethreshold and stage 3 threshold retinopathy of prematurity.

Purpose: To analyze the structural outcomes of zone I prethreshold and stage 3 threshold retinopathy of prematurity following laser ablation.

Patients And Methods: This nonrandomized observational case series evaluated 71 eyes of 36 infants who weighed less than 1,250 g at birth. Infants were treated at either prethreshold or threshold severity.

[Determination of serum semicarbazide-sensitive amine oxidase activity in diabetic retinopathy in type-2 diabetes].

Introduction: Recent data suggest that the copper-containing semicarbazide-sensitive amine oxidase enzyme (SSAO) may play a role in vascular endothelial damage through conversion of certain endogenous monoamines, like methylamine into cytotoxic aldehydes, hydrogen peroxide and ammonia. SSAO is present in various human tissues and in the serum. Elevated SSAO activities have been reported in patients with both types of diabetes mellitus.

MRI for the evaluation of scleral invasion and extrascleral extension of uveal melanomas.

Aim: To study the diagnostic value of MRI for the detection of scleral infiltration and extrascleral extension of uveal melanoma.

Materials And Methods: Twelve consecutive patients with clinically suspected large uveal melanoma were examined by MRI. All of the patients underwent enucleation or exenteration.