Publications by authors named "Gwyneth A Hutchinson"
Article Synopsis
- Spaceflight triggers an immune response in astronauts, which was analyzed during the SpaceX Inspiration4 mission using various data types, including single-cell and biochemical analysis.
- Researchers identified a "spaceflight signature" in gene expression linked to processes like oxidative phosphorylation, immune function, and inflammation, found across multiple datasets.
- Key findings include up-regulation of specific immune markers in T cells, long-term suppression of certain MHC class I genes, and changes in infection-related immune pathways due to shifts in the microbiome.
The integration of biology and spacefaring has led to the development of three interrelated fields: Astrobiology, Bioastronautics, and Space Bioprocess Engineering. Astrobiology is concerned with the study of the origin, evolution, distribution, and future of life in the universe, while Bioastronautics focuses on the effects of spaceflight on biological systems, including human physiology and psychology. Space Bioprocess Engineering, on the other hand, deals with the design, deployment, and management of biotechnology for human exploration.
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