Publications by authors named "Gwenaella Rescourio"
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Synopsis of recent research by authors named "Gwenaella Rescourio"
- Gwenaella Rescourio's research primarily focuses on the discovery and evaluation of novel pharmacological agents targeting specific proteins involved in pain and cancer, particularly the Na1.7 sodium channel and the Mcl-1 antiapoptotic protein.
- Notable findings include the development of pyridyl urea sulfonamide inhibitors of Na1.7 which demonstrate promising selectivity and reduced off-target effects, as well as macrocyclic Mcl-1 inhibitors that show robust efficacy in myeloma models.
- Additionally, her work encompasses synthetic methodologies for complex organic compounds, including radical cyclization techniques and palladium-catalyzed reactions, showcasing her contributions to both medicinal chemistry and synthetic organic chemistry.
