Non-invasive structural and metabolic retinal markers of disease activity in non-proliferative diabetic retinopathy.

Purpose: Metabolic and structural microvascular retinal alterations are essential components in diabetic retinopathy (DR). The present study aimed to measure changes at different stages of non-proliferative DR (NPDR) and to explore interactions of imaging-based metrics.

Methods: This cross-sectional, cohort study included 139 eyes from 80 diabetic patients.