Impact of prenatal life on the risk of developing epilepsy.

Epilepsy is an enduring predisposition of the brain to generate epileptic seizures and has a worldwide incidence of 21-24 per 100,000 cases among children. Epilepsy is a multifactorial disease; however, certain risk factors are predicted to increase its incidence. Abnormal brain development during prenatal life, particularly during the last trimester, is considered to play a crucial role in the development of certain neurological disorders.

No Good Time Without Drugs: Qualitative Study Among Nightlife Attendees in Tbilisi, Georgia.

Introduction: Individuals who visit nightclubs and electronic dance music (EDM) festivals tend to use psychoactive substances, often multiple substances, in this setting and are at risk of serious negative health effects. This paper aims to explore respondents' experiences and perceptions in order to have a better understanding of patterns and motives related to psychoactive substance use and high-risk behaviours in EDM event attendees.

Methods: In-depth and focus group interviews with 30 EDM event attendees who reported psychoactive substance use at nightlife events.

CORRELATION OF THERMAL PAIN PERCEPTION AND HOSTILITY IN MALES AND FEMALES DURING PHYSIOLOGIC STARVATION.

The phenomenon of pain remains one of the most important challenges in medicine and biology, which often causes disability in humans and worsens the quality of life. The pain is a variable, subjective experience, and it is impossible to fully understand it without getting to know the physiological mechanisms beyond sensory damage of the tissues. There are some gender differences in pain perception, particularly, females tend to be more sensitive towards experimental pain.

SENSITIVITY TO MECHANICAL PAIN BASED ON SATIETY LEVELS IN WOMEN.

The recent data have shown that in addition to biological and psychosocial mechanisms, individual pain perception can be altered by satiety level as well. Some studies confirm that there is a relationship between being fed by sucrose and hyperalgesia in animals, while others show that ketogenic diet can be associated with decreased pain sensitivity to thermal stimuli. It can be argued that the effect of satiety level on pain perception is mediated by gastrointestinal hormones and endogenous opioids.