Publications by authors named "Guy Watanabe"
Article Synopsis
- Intrarenal dopamine helps protect against diabetic nephropathy in early-stage diabetes by reducing glomerular hyperfiltration, oxidative stress, inflammation, and fibrosis in mice models.
- The study used benserazide to investigate the effects of peripheral dopamine on kidney function in spontaneously diabetic Torii rats, showing that lower peripheral dopamine levels worsen renal dysfunction.
- Findings reveal that peripheral dopamine plays a crucial role in controlling oxidative stress and kidney performance during the early stages of diabetic nephropathy, evidenced by its effect on markers of renal dysfunction.
Introduction: Fatigue is reportedly associated with a poor prognosis in dialysis patients. The aim of the present study was to investigate whether fatigue on dialysis days or non-dialysis days is associated with mortality in patients on chronic hemodialysis.
Methods: This was a prospective study of 134 hemodialysis patients.
Article Synopsis
- - The report discusses a 38-year-old Japanese woman who developed systemic lupus erythematosus (SLE) after contracting COVID-19, showing symptoms like skin issues, joint pain, and positive autoantibodies.
- - The patient met classification criteria for SLE, experienced renal involvement, and improved with immunosuppressive treatment.
- - A literature review found 10 similar cases, suggesting that SLE should be considered for patients with ongoing nonspecific symptoms post-COVID-19, especially with hematologic and renal symptoms.
Intestinal Behçet disease associated with myelodysplastic syndrome accompanying trisomy 8 successfully treated with abdominal surgery followed by hematopoietic stem cell transplantation: A case report.
Tomoyuki Asano Shuzo Sato Makiko Yashiro Furuya Hiroshi Takahashi Akiko Shichishima-Nakamura Guy Watanabe Hiroshi Watanabe
Medicine (Baltimore)
November 2019
Rationale: Intestinal Behçet disease (BD) with myelodysplastic syndrome (MDS) is a rare condition that is resistant to various immunosuppressive therapies. Several cases in which hematopoietic stem cell transplantation (HSCT) was effective for intestinal BD with MDS accompanying trisomy 8 have been reported.
Patient Concerns: We report an 18-year-old female with a 7-year history of BD.