N-of-1 randomized trials to assess the efficacy of gabapentin for chronic neuropathic pain.

Objective: The objective of this study was to compare the efficacy of gabapentin with placebo for neuropathic pain at the individual and population levels.

Design: This study used an n-of-1 trial methodology with three double-blind, randomized, crossover comparisons of gabapentin with placebo.

Setting: This study was carried out at specialist outpatient clinics at two Australian hospitals.

Developing prosthetic weight bearing in a knee disarticulation amputee.

An essential component of prosthetic training in amputees is to achieve full weight bearing through the prosthesis. The end-bearing nature of the intact femur in an individual with a knee disarticulation amputation (KDA) offered a rare opportunity to examine this component. The purpose of this case study was to describe the weight-bearing development in a temporary prosthesis.