Publications by authors named "Guy Hoffmann"

Background: Until now, studies about body position and nocturnal breathing abnormalities have been restricted to comparing supine versus lateral positions.

Objectives: In this retrospective study, we systematically evaluated the effect of body position on nocturnal breathing in 105 patients with a sleep apnea hypopnea syndrome (SAHS).

Methods: All the patients had an apnea hypopnea index > 10/h, as judged from polysomnography performed in the sleep laboratory.

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Objective: The lack of distinction in the clinical use of terms like fatigue and sleepiness is an important issue. While both fatigue and sleepiness can potentially be associated with nonrestorative sleep (NRS) complaints, their relationships are still poorly described. We propose to use Rasch analysis-based methods to study the interrelations of fatigue, sleepiness and NRS.

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The status of chronic fatigue syndrome (CFS) is still under debate. Mainstream views still often consider it as an undetected primary sleep disorder or as the psychosomatic expression of a related anxiety or depression syndrome. Both primary sleep disorder and CFS are often related to unrefreshing sleep and affective daytime symptoms.

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It is presently unclear whether chronic fatigue syndrome (CFS) patients exhibit daytime sleepiness in addition to fatigue. Both, fatigue, such as that seen in CFS patients, and excessive daytime sleepiness, such as in sleep apnea-hypopnea syndrome (SAHS), remain poorly understood. Both daytime conditions are generally related to unrefreshing sleep and show affective symptoms.

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Background/aims: One of the core symptoms of the chronic fatigue syndrome (CFS) is unrefreshing sleep and a subjective sensation of poor sleep quality. Whether this perception can be expressed, in a standardized questionnaire as the Pittsburgh Sleep Quality Index (PSQI), has to our knowledge never been documented in CFS. Furthermore, correlations of subjective fatigue, PSQI, affective symptoms and objective parameters such as sleep efficiency are poorly described in the literature.

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Study Objectives: As the effects of general slowness and decreased attentional capacity on higher executive attention have not been fully taken into account in the sleep apnea literature, we statistically controlled for basic attentional performance in evaluating executive attention per se in sleep apnea patients.

Design: A case-controlled design was used with comparison of basic and executive attentional tasks.

Participants: Thirty-six polysomnographically diagnosed patients (mean apnea-hypopnea index = 60.

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Since the magnitude of the first-night effect has been shown to be a function of medical conditions and of settings in which polysomnographies are performed, it is essential to evaluate the habituation phenomenon in each case in order to determine the optimal recording methodology. A first-night effect was evidenced in certain cases of chronic fatigue syndrome, but not in others. To clarify this issue, a large group of patients with chronic fatigue syndrome who had no primary sleep disorders were selected and recorded for two consecutive nights in a hospital sleep unit.

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Alcohol detoxification is accompanied by sustained difficulties in sleep initiation and maintenance. These difficulties are thought to be an important cause of relapse to alcohol use. However, the treatment of sleep problems with hypnotic drug is made difficult by cross-tolerance between benzodiazepines and alcohol.

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