Environmental sustainability in urologic practices: a systematic review.

Purpose: The aim of this systematic review is to assess the environmental impact of urologic procedures and equipment (P), specifically comparing emissions and waste generation between single-use and reusable devices (I and C), while also exploring strategies for emission reduction and providing relevant recommendations for sustainable practices in urology.

Methods: The review registered to PROSPERO (ID: CRD42024576865) and adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. A systematic search was conducted to identify studies addressing sustainability, carbon footprint, and environmental impact in urology.

Novel inflammatory biomarkers for discriminating vascular involvement in Behçet's syndrome: evaluating SII, SIRI, and NPAR.

Objective: This study aims to investigate discriminatory ability of the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Neutrophil Percentage-to-Albumin Ratio (NPAR), in differentiating Behçet's Syndrome (BS) organ involvements from mucocutaneous involvement.

Methods: This retrospective cohort study analyzed 436 patients diagnosed with BS from 2018 to 2023. Patients were categorized into three groups based on organ involvement: vascular, only mucocutaneous, and other organ involvement.

Effect of biological treatment on the thiol/disulfide parameters in patients with axial spondyloarthritis.

Objective: Aim of this study is to compare the thiol/disulfide variables before treatment, at the 3 and 6 months of biologic treatment in patients with axSpA.

Materials & Methods: Consecutive patients with axial spondyloarthritis to whom biologic treatment was initiated in our clinic were enrolled upon consent. Demographics, clinical characteristics, laboratory parameters and treatment agents were collected.

Sarcopenia and sarcopenic obesity: Their association with postoperative outcomes in patients with hip fractures.

Background: Sarcopenia, characterized by age-related loss of muscle mass and function, significantly impacts the quality of life of older adults. This condition is prevalent among elderly patients with hip fractures.

Objective: To investigate the association of sarcopenia and sarcopenic obesity with mortality and length of hospital stay in patients admitted for hip fracture.

Traction-related urinary complications in hip arthroscopy using a perineal post: Prevalence, risk factors, and outcomes.

Background: Femoroacetabular impingement syndrome (FAIS) is a leading cause of chronic hip pain in young adults, often treated with hip arthroscopy. While effective, the procedure involves traction with a perineal post that can impact the urogenital system. This study aims to evaluate urinary function changes in patients undergoing hip arthroscopy for FAIS.

Pulsed Thulium: YAG laser for the management of Urolothiasis: a systematic review from the EAU section of endourology.

Introduction: In an effort to address the limitations of current lasers, pulsed-waved Thulium: YAG laser devices were released. The purpose of this systematic review is to present all existing data, arising exclusively from human studies and clinical practice, regarding the endourological applications of the new pulsed-waved Thulium: YAG laser technology in stone disease management.

Patients And Methods: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement, three databases (PubMed, Scopus and Cochrane) were thoroughly investigated from inception to 30 December 2024.

HoLEP versus ThuFLEP in men with very large prostates (> 175 ml).

Purpose: We aimed to demonstrate and compare the efficacy and safety of HoLEP and ThuFLEP procedures in patients with very large prostates (> 175 ml).

Methods: Patients with prostates larger than 175 ml who underwent HoLEP (Group 1, n = 72) and ThuFLEP (Group 2, n = 85) for benign prostatic obstruction (BPO) were retrospectively analysed. Perioperative, postoperative functional outcomes and complications were analysed and compared.

Preoperative 'target marking' on the skin reduces radiation exposure and total surgical duration in surgically treated pediatric supracondylar humerus fractures; a case-control clinical study.

Background: Primary treatment for supracondylar humerus fractures SCHF involves a closed reduction and fixation with K-wires. The aim of this study is to investigate whether a target marking of the humerus is effective in reducing operation duration and radiation exposure in surgically treated pediatric supracondylar humerus fractures.

Methods: Patients treated with a closed reduction and percutaneous pinning (CRPP) for a SCHF between 2019 and 2023 were included.

Longitidunal changes in accommodation amplitude after strabismus surgery.

Purpose: To investigate changes in accommodation amplitude (AA) after strabismus surgery.

Methods: The medical records of patients who underwent full-tendon tenotomy on at least one rectus muscle between January 2023 and July 2023 were reviewed retrospectively. AA was evaluated objectively and monocularly with the autorefractometry (Tonoref III, ARK-1a, NIDEK Co Ltd, Gamagori, Japan).

Comparison of Cerebral Blood Circulation of Fetuses with Congenital Heart Disease with Healthy Fetuses.

Background: The effect of congenital cardiac malformation on fetal cerebral circulation has not been well known. This study aimed to compare the cerebral blood circulation of fetuses with congenital heart disease (CHD) with healthy fetuses.

Methods: This prospective cohort study included 37 pregnant women who presented to the gynecology and obstetrics department of department of Farabi Hospital, Faculty of Medicine, Karadeniz Technical University for anomaly screening in the second trimester.

Patient-derived cornea organoid model to study metabolomic characterization of rare disease: aniridia-associated keratopathy.

Background: Aniridia is a rare panocular disease caused by gene mutation in the PAX6, which is essential for eye development. Aniridia is inherited in an autosomal dominant manner, but its phenotype can vary significantly among individuals with the same mutation. Animal models, such as drosophila, zebrafish, and rodents, have been used to study aniridia through Pax6 deletions.

Clinical and molecular genetic characteristics of patients with hereditary hypophosphatemia.

Background: Hereditary hypophosphatemia (HH), is a rare condition related to decreased renal tubular phosphate reabsorption. Although X-linked hypophosphatemia or PHEX gene variant is the most frequent cause of HH, recent advances in next-generation sequencing (NGS) techniques enable the identification of genetic etiologies as a whole.

Objective: To identify genetic causes of HH using various genetic testing methods and to compare clinical features between FGF23-dependent and FGF23-independent HH groups.

Resistance to Epoetin-Stimulating Agents in Children Receiving Renal Replacement Therapy.

The incidence of anemia increases with the stage of chronic kidney disease (CKD). Erythropoietin (EPO) deficiency is a common cause of anemia in CKD. Erythropoietin-stimulating agents (ESAs) are the mainstay of the treatment.

Patient satisfaction with health care services in Turkiye: A glimpse from nationwide Ministry of Health database.

Objective: Patient satisfaction refers to the degree to which patients' expectations from health care services are met and is a critical indicator used to measure the overall quality of this service. This study aims to analyze overall patient satisfaction and regarding factors in our country, providing valuable insights for policymakers, clinicians, and researchers who aim to improve the quality of health care services and patient outcomes. Furthermore, as a nationwide assessment, this study reveals the potential of big data analytics in health services.

Do Intact Collateral Ligaments Play a Role in the Overall Clinical and Radiological Results of Rotating Hinge Knee Arthroplasties?

Background: Rotating hinge knee arthroplasty (RHKA) implants are often utilized as a salvage procedure in cases where bone stock is compromised. The aim of this retrospective study was to investigate whether residual collateral ligament integrity affects functional and radiographic outcomes in patients undergoing revision surgery with RHKA.

Methods: Patients treated with RHKA between 2011 and 2021 were eligible.

Long-term in vivo comparison of histopathological effects of two barbed sutures and a conventional suture material in a rat model.

Background: Urological repairs require secure suturing for effective healing. While conventional sutures like Vicryl are common, barbed sutures offer knotless options. This study aims to compare the histopathological effects of barbed and conventional sutures on the bladder.

OrganoLabeler: A Quick and Accurate Annotation Tool for Organoid Images.

Organoids are self-assembled 3D cellular structures that resemble organs structurally and functionally, providing platforms for molecular and therapeutic studies. Generation of organoids from human cells often requires long and costly procedures with arguably low efficiency. Prediction and selection of cellular aggregates that result in healthy and functional organoids can be achieved by using artificial intelligence-based tools.

Real-world data on direct oral anticoagulants in BCR::ABL1-negative myeloproliferative neoplasms (MPNs): a multicenter retrospective study on behalf of scientific subcommittee on MPNs for Turkish society of hematology.

BCR::ABL1-negative myeloproliferative neoplasms (MPNs) pose a substantial risk of thrombosis, leading to significant morbidity and mortality. Anticoagulant therapy, historically based on vitamin K antagonists (VKAs), has limitations in preventing recurrent thrombotic events and managing bleeding complications. Direct oral anticoagulants (DOACs) offer a potential alternative with improved pharmacokinetics and compliance.

The Effects of Memantine on Cisplatin-Induced Ototoxicity.

Introduction: We aimed to investigate electrophysiologically and histopathologically, the protective effects of intratympanic memantine, an N-methyl-D-aspartate receptor antagonist, on ototoxicity caused by cisplatin, an anti-neoplastic agent used in many types of cancer.

Methods: Thirty-seven guinea pigs with a normal auditory function were randomly allocated to group 1 (cisplatin; n = 8), group 2 (memantine; n = 8), group 3 (cisplatin + memantine; n = 8), group 4 (cisplatin + physiological serum [PS]; n = 8), and group 5 (control; n = 5). Auditory assessments were conducted using distortion product otoacoustic emissions (DPOAE) within a frequency range of 1-32 kHz and auditory brainstem responses (ABRs) within 8-32 kHz.

A systematic review on urolithiasis in children with neurological disorders.

Purpose: Advancements in medical treatments and increased access to healthcare have significantly extended the life expectancy of children with neurological disorders. However, this has also led to a higher incidence of secondary health issues, such as nephrolithiasis. This review aims to analyze the risk factors, management, and treatment outcomes for stone disease in children with neurological disorders and focus on specific risk factors such as immobilization, urinary tract infections, and metabolic abnormalities to identify key points in the occurrence of nephrolithiasis.