Physical fitness is associated with neural activity during working memory performance in major depressive disorder.

Background: Deficits in cognition like working memory (WM) are highly prevalent symptoms related to major depressive disorder (MDD). Neuroimaging studies have described frontoparietal abnormalities in patients with MDD as a basis for these deficits. Based on research in healthy adults, it is hypothesized that increased physical fitness might be a protective factor for these deficits in MDD.

Co-creation environment with cloud virtual reality and real-time artificial intelligence toward the design of molecular robots.

This paper describes the design philosophy for our cloud-based virtual reality (VR) co-creation environment (CCE) for molecular modeling. Using interactive VR simulation can provide enhanced perspectives in molecular modeling for intuitive live demonstration and experimentation in the CCE. Then the use of the CCE can enhance knowledge creation by bringing people together to share and create ideas or knowledge that may not emerge otherwise.

Effects of adaptive and non-adaptive three-week executive control training on interference control: Evidence from the N2, CRN, and ERN.

The current pilot study investigated if interference control can be improved by a three-week at-home training comprising a flanker and a n-back task in healthy adults, thus exploring the training's suitability for future clinical application, i.e. as a treatment augmentation for psychological disorders.

Adaptation of Patterns of Motile Filaments under Dynamic Boundary Conditions.

Boundary conditions are important for pattern formation in active matter. However, it is still not well-understood how alterations in the boundary conditions (dynamic boundary conditions) impact pattern formation. To elucidate the effect of dynamic boundary conditions on the pattern formation by active matter, we investigate an gliding assay of microtubules on a deformable soft substrate.

The subforaminal stenosis headache.

The clinical picture of the so-called subforaminal stenosis headache (Gutmann) and its surgical treatment (Roesner) have been presented. We have analyzed our findings in 119 patients and 55 operations. The clinical picture is characterized by increasing pain in the upper cervical and occipital region which in later stages may be accompanied also by other symptoms like disturbances of concentration, memory, libido, and potency, as well in some cases by symptoms similar to those of a secondary chronic myelopathy.

[The biomechanical pathogenesis and differentiated therapy of cervical headache (author's transl)].

Dysfunction in the upper region of the cervical vertebral column is largely to be regarded as the primary disorder from which secondary anatomical substrates, especially degenerative manifestations, develop. We must shift our attention from pathomorphology to function. There are two main types of disordered vertebral function which may lead to headache in many cases: 1.