Publications by authors named "Gutierrez H"

The effects of mechanical vibrations on control system stability could be significant in control systems designed on the assumption of rigid-body dynamics, such as launch vehicles. Vibrational loads can also cause damage to launch vehicles due to fatigue or excitation of structural resonances. This paper investigates a method to control structural vibrations in real time using a finite number of strain measurements from a fiber Bragg grating (FBG) sensor array.

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  • Protein/protein interactions (PPI) are important for brain functions, but their use as drug targets for brain disorders is not fully explored.
  • A small molecule called compound 1028 has been identified that targets the FGF14/Na1.6 PPI and affects the channel's activity, resulting in increased excitability of neurons.
  • Administering compound 1028 can enhance motivation under challenging conditions, and its effects are linked to changes in dopamine levels in the brain, suggesting a new way to impact behaviors related to neuropsychiatric disorders.
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We have investigated the Raman spectrum and excitonic effects of the novel 2D TaNiTe structure. The monolayer is an indirect band gap semiconductor with an electronic band gap value of 0.09 and 0.

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: We compared thoracic electrical impedance tomography (EIT) with slow vital capacity (SVC) to determine if EIT could monitor pulmonary function in ALS patients longitudinally. : Of 32 ALS patients and 32 age- and sex-matched healthy controls (HCs) initially enrolled in the Pulmonary Function via Impedance Tomography (PuFIT) study, 22 ALS and 20 HCs returned for a follow-up visit ∼3.9 months later.

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  • - The study examined trunk impact dynamics in goalball players using inertial sensors, focusing on changes in impact workloads between the first and second halves of a match.
  • - Six players wore accelerometers during a game, revealing that the first half had significantly more total impacts and higher intensity impacts compared to the second half, where players experienced a decrease in intensity and impact levels.
  • - Findings suggest that game intensity is linked to the number of impacts, pointing to a potential need for targeted training to balance workload and performance in goalball players.
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  • * Fifteen trained trail runners (10 males and 5 females) participated in a VK race, utilizing advanced equipment to measure their physiological responses, revealing significant differences in multiple respiratory and cardiovascular variables between genders and performance levels.
  • * Key performance indicators such as oxygen consumption and carbon dioxide production were identified, highlighting the importance of muscular adaptations and respiratory capacity for success in these intense, short-duration races.
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In athletic training and research, the evaluation of sprint speed is widely used, and its accurate measurement is especially demanding. High-cost photocells are the gold-standard system for sprint time assessment, although low-cost smartphone applications can be a suitable option. This study assesses the validity and reliability of an application to measure sprint time compared to photocells.

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Background: Factors associated with severe COVID-19 infection have been identified; however, the impact of infection on longer-term outcomes is unclear. The objective of this study was to examine the impact of COVID-19 infection on the trajectory of lung function and nutritional status in people with cystic fibrosis (pwCF).

Methods: This is a retrospective global cohort study of pwCF who had confirmed COVID-19 infection diagnosed between January 1, 2020 and December 31, 2021.

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Oxidative stress has long been postulated to play an essential role in aging mechanisms, and numerous forms of molecular damage associated with oxidative stress have been well documented. However, the extent to which changes in gene expression in direct response to oxidative stress are related to actual cellular aging, senescence, and age-related functional decline remains unclear. Here, we ask whether HO-induced oxidative stress and resulting gene expression alterations in prostate epithelial cells in vitro reveal gene regulatory changes typically observed in naturally aging prostate tissue and age-related prostate disease.

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Background: In patients with in-stent restenosis (ISR) bioresorbable vascular scaffolds (BVS) provide similar results to drug-coated balloons (DCBs) but are inferior to drug-eluting stents (DES) at 1 year. However, the long-term efficacy of BVS in these patients remains unknown.

Objectives: This study sought to assess the long-term safety and efficacy of BVS in patients with ISR.

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Rabal-Pelay, J, Gutiérrez, H, Bascuas, P-J, Pareja-Blanco, F, and Marco-Contreras, LA. Load-velocity relationship in the Bulgarian split-squat exercise. J Strength Cond Res 38(11): 1849-1853, 2024-The objective of the current research was to analyze the load-velocity relationship in the Bulgarian split-squat (BSS) exercise and to compare these relationships between the dominant and nondominant legs.

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Transmembrane peptides play important roles in many biological processes by interacting with lipid membranes. This study investigates how the transmembrane domain of the influenza A virus M2 protein, M2TM, affects the structure and mechanics of model lipid bilayers. Atomic force microscopy (AFM) imaging revealed small decreases in bilayer thickness with increasing peptide concentrations.

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This study investigated biomechanical assessments in trail running, comparing two wearable devices-Stryd Power Meter and GARMIN. With the growing popularity of trail running and the complexities of varied terrains, there is a heightened interest in understanding metabolic pathways, biomechanics, and performance factors. The research aimed to assess the inter- and intra-device agreement for biomechanics under ecological conditions, focusing on power, speed, cadence, vertical oscillation, and contact time.

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Background: Optimal strategies to manage embolization of transcatheter aortic valve implantation (TAVI) devices are unclear; valve-in-valve (ViV) is often used. We aimed to describe through one-single center experience its rate, causes, consequences, and management as well as the rate and relevance of commissural alignment (CA) in this context.

Methods: We identified across 1038 TAVI cases, those cases requiring ViV for the management of first device embolization.

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Sánchez-Sabaté, J, Gutiérrez, H, Marco-Contreras, LA, Younes-Egana, O, Gonzalo-Skok, O, and Piedrafita, E. Influence of vertical-oriented vs. horizontal-oriented combined strength training in young basketball players.

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Objective: We sought to determine whether thoracic electrical impedance tomography (EIT) could characterize pulmonary function in amyotrophic lateral sclerosis (ALS) patients, including those with facial weakness. Thoracic EIT is a noninvasive, technology in which a multi-electrode belt is placed across the chest, producing real-time impedance imaging of the chest during breathing.

Methods: We enrolled 32 ALS patients and 32 age- and sex-matched healthy controls (HCs) without underlying lung disease.

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Layered TaMTe (M = Pd, Ni) has emerged as a platform to study 2D topological insulators, which have exotic properties such as spin-momentum locking and the presence of Dirac fermions for use in conventional and quantum-based electronics. In particular, TaNiTe has been shown to have superconductivity under pressure and is predicted to have second-order topology. Despite being an interesting material with fascinating physics, the detailed crystalline and phononic properties of this material are still unknown.

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New and promising variables are being developed to analyze performance and fatigue in trail running, such as mechanical power, metabolic power, metabolic cost of transport and mechanical efficiency. The aim of this study was to analyze the behavior of these variables during a real vertical kilometer field test. Fifteen trained trail runners, eleven men (from 22 to 38 years old) and four women (from 19 to 35 years old) performed a vertical kilometer with a length of 4.

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Real-time flight controllers are becoming dependent on general-purpose operating systems, as the modularity and complexity of guidance, navigation, and control systems and algorithms increases. The non-deterministic nature of operating systems creates a critical weakness in the development of motion control systems for robotic platforms due to the random delays introduced by operating systems and communication networks. The high-speed operation and sensitive dynamics of UAVs demand fast and near-deterministic communication between the sensors, companion computer, and flight control unit (FCU) in order to achieve the required performance.

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Introduction: The First UN Decade of Action for Road Safety (2011-2020) ended with most low/middle-income countries (LMICs) failing to reduce road traffic deaths. In contrast, Brazil reported a strong decline starting in 2012. However, comparisons with global health statistical estimates suggest that official statistics from Brazil under-report traffic deaths and overestimate declines.

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Background: Previously, we adapted a mobile health platform (Genia) to the needs of patients and families in a pediatric CF center in the United States. In this feasibility study, we tested the impact of Genia on measures of patient-centered care.

Methods: In a one-group pre-post study with adolescents with CF and caregivers of children with CF, we tested Genia's effect over 6 months on patient satisfaction with chronic illness care (PACIC) and shared decision-making (CollaboRate).

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Circulating microRNAs (c-miRNAs) during pregnancy could provide information regarding the functional status of the mother and fetus. However, it remains unclear which pregnancy-related processes are actually reflected by changes c-miRNAs. Here, we used large-scale c-miRNA profiling of maternal plasma during and post-pregnancy, and compared it with that of non-pregnant women.

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