Publications by authors named "Guthy I"

Malnutrition and inflammatory bowel disease (IBD) are interrelated conditions. Our aim was to assess the prevalence of malnutrition, to compare anthropometric parameters in the evaluation of nutritional status in pediatric IBD, and to investigate the association between anthropometric parameters and disease activity indices (AI). Pediatric patients with newly diagnosed IBD recorded between 2010 and 2016 in the Hungarian Pediatric IBD Registry were included in this cross-sectional study.

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According to the Porto criteria, upper endoscopy and ileocolonoscopy with histology for patients with pediatric inflammatory bowel disease (pIBD) are recommended with small bowel imaging (SBI). We aimed to evaluate the adherence to the Porto criteria and biopsy sampling practice and to evaluate the diagnostic yield of magnetic resonance enterography (MRE) first time in a nationwide pIBD inception cohort. Newly diagnosed pIBD cases (ages 0-18 years) are registered in the prospective, nationwide Hungarian Paediatric IBD Registry (HUPIR).

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Article Synopsis
  • The study evaluated the usage of a "no-biopsy" diagnostic approach for coeliac disease (CD) among pediatric gastroenterologists in Central Europe, in light of new ESPGHAN guidelines that allow diagnosis without duodenal biopsy if specific criteria are met.
  • Medical records from 653 children diagnosed with CD in 2016 showed that only 20.6% of symptomatic patients used the "no-biopsy" method, despite approximately 60% being eligible for it based on high transglutaminase antibody levels (TGA).
  • The study found that children diagnosed without biopsies experienced more signs of malabsorption, but there were no significant delays in diagnosis compared to those who underwent biopsies
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Objectives: Predicting short-term relapses and long-term prognosis is of utmost importance in paediatric inflammatory bowel disease (IBD). Our aim was to investigate the short-term disease outcome and medication during the first year in a paediatric incident cohort from Hungary. In addition, association laboratory markers and disease activity indices with short-term disease outcome and medication were analysed.

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Introduction: In severe short bowel syndrome, as a result of the natural adaptation, the bowel becomes overdilated, this interferes with the persitalsis and may lead to stasis, bacterial translocation and sepsis. At present two techniques are used to improve peristalsis. The Bianchi procedure is technically challenging, the Serial Transverse Enteroplasty (STEP) is easy however it results in an aphysiological ultrastructure altering the orientation of the muscle fibres.

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Aim: Spiral Intestinal Lengthening and Tailoring (SILT) invented by our team is a new technique that offers minimal mesenteric handling and a more physiological result compared to the STEP procedure. Its feasibility has been tested in animal models and now we report the first successful human application in extreme short bowel syndrome.

Materials And Methods: A 3-year-old girl suffered subtotal loss of her small bowel and ileocaecal junction as a result of midgut volvulus.

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Objectives: The aim of the study was to evaluate the incidence, baseline disease characteristics, and disease location based on the Paris classification in pediatric inflammatory bowel disease (IBD) in the Hungarian nationwide inception cohort. In addition, 1-year follow-up with therapy was analyzed.

Methods: From January 1, 2007 to December 31, 2009, newly diagnosed pediatric patients with IBD were prospectively registered.

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Article Synopsis
  • The study evaluated the role of esophagogastroduodenoscopy (EGD) in diagnosing upper gastrointestinal (UGI) involvement in children with inflammatory bowel disease (IBD), particularly focusing on Crohn's disease (CD) and ulcerative colitis (UC).
  • During the study from 2007 to 2009, 420 children were diagnosed with IBD, with a prevalence of 63% CD and 31% UC, and EGD was performed on 56% of patients, revealing significant UGI lesions in many.
  • The findings indicated that there is a notable UGI involvement in children with both CD and UC, with one-third of CD patients showing significant lesions, but EGD provided a definitive diagnosis for
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