Cross-reactive IgE antibody responses to tropomyosins from Ascaris lumbricoides and cockroach.

Background: Evidence indicates that infection with Ascaris lumbricoides may promote development of allergy and asthma.

Objective: To study the role of tropomyosin, a pan-allergen in invertebrates, in IgE responses to A lumbricoides.

Methods: Recombinant A lumbricoides and Periplaneta americana tropomyosins were expressed in Pichia pastoris.

Toxocara canis: impact of preweaning nutritional deprivation on the pathogenesis of pneumonia in the mouse.

The present study was conducted to better understand the immure response to Toxocara canis pneumonia in mice with preweaning nutritional deprivation. Breast-fed Swiss mice, undernourished due to large litter size (up to 15 pups) and paired controls with only 5-8 pups were used. At 21 days old, both groups were infected with T.