Publications by authors named "Gustavo Mora Navarro"

Article Synopsis
  • A systematic review and meta-analysis was performed to compare proactive therapeutic drug monitoring (TDM) with conventional management in patients with inflammatory bowel disease (IBD) receiving anti-tumor necrosis factor (anti-TNFα) treatment.
  • Nine studies were assessed, indicating that proactive TDM does not significantly improve maintenance of clinical remission compared to standard treatment, although it may enhance treatment durability and reduce some adverse effects and surgical needs.
  • The findings suggest that proactive TDM is not superior to conventional management for IBD patients, meaning it is not currently recommended.
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Background: Latent autoimmune diabetes in adults (LADA) is a type of diabetes mellitus showing overlapping characteristics between type 1 Diabetes Mellitus and type 2 Diabetes Mellitus (T2DM), and autoimmunity against insulin-producing pancreatic cells. For its diagnosis, at least one type of anti-pancreatic islet antibody (GADAb is the most common) is required. Many authors recommend performing this measure in all newly diagnosed patients with DM, but it is not possible in Primary Health Care (PHC) due to its high cost.

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Introduction: This study aimed to confirm the usefulness of basal insulin analogue plus oral antidiabetic drugs (OADs) for type 2 diabetes (T2D) patients inadequately controlled with premixed insulin with/without OADs and assess the role of dipeptidyl peptidase-4 (DPP-4) inhibitors within this regimen in clinical practice.

Methods: Spanish retrospective observational study that included 186 T2D patients with glycosylated hemoglobin (HbA1c) >7% (53 mmol/mol) despite premixed insulin with/without OADs who had been switched to basal insulin analogue plus OADs. Study data describing the situation before the treatment switch and 6 months later was retrospectively retrieved from patients' medical charts.

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Objective: We aimed to know how the directive teams perceive the implementation of organizational procedures in relation with the health care management in the primary care setting.

Design: Multicentre cross-sectional descriptive study.

Setting: Area 11 Madrid Primary Care Service, Spain.

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