New biocompatible highly purified collagen gel for therapeutic renal artery embolization.

Objectives: To evaluate the effectiveness and safety of a new purified collagen gel with specific properties for renal artery embolization in an experimental model in dogs.

Methods: The new gel was prepared from type I bovine tendon collagen, highly purified to eliminate immunogenicity, and reconstituted through extensive dialysis in distilled water without the addition of glutaraldehyde. The study was conducted on 16 mongrel dogs that underwent random embolization of the renal artery.