Arterial stiffness predicts amputation and death in patients with chronic limb-threatening ischemia.

Objective: Arterial stiffness indices predict cardiovascular outcomes in patients with coronary or kidney disease; however, there is little data on the prognostic value of arterial stiffness in patients with advanced peripheral arterial disease. We determined whether arterial stiffness indices predict the outcomes of major amputation or death in patients with chronic limb-threatening ischemia (CLTI).

Methods: Arterial stiffness was prospectively measured using brachial oscillometry in patients with CLTI.