Therapeutic hypothermia as a neuroprotective strategy in newborns with perinatal asphyxia-case report.

Background: Perinatal asphyxia is a public health problem and the third major cause of death among children under 5 years.

Objective: Two clinical cases of newborns with perinatal asphyxia submitted to therapeutic hypothermia and the follow-up of their motor development after hospital discharge have been reported.

Methods: This retrospective case report study included two newborns with hypoxic-ischemic encephalopathy due to perinatal asphyxia who received a hypothermia protocol at the neonatal intensive care unit (NICU).