Biosynthesis of cyanogenic glucosides in and the evolution of oxime-based defenses.

Lima bean, , is a crop legume that produces the cyanogenic glucosides linamarin and lotaustralin. In the legumes and , the biosynthesis of these two α-hydroxynitrile glucosides involves cytochrome P450 enzymes of the CYP79 and CYP736 families and a UDP-glucosyltransferase. Here, we identify CYP79D71 as the first enzyme of the pathway in , producing oximes from valine and isoleucine.