Publications by authors named "Gustavo B Lamy"
Article Synopsis
- * In experiments with adult female Wistar rats, both intravenous and topical administration of angiotensin-(1-7) significantly increased intravesical pressure (IP) without affecting mean arterial pressure (MAP), heart rate (HR), or renal conductance (RC).
- * Analysis showed that Mas receptors and ACE-2 are expressed in the bladder, indicating that angiotensin-(1-7) not only affects the UB but may also be locally produced there.
Article Synopsis
- Central micturition involves a complex neuronal circuit that regulates bladder control, with specific stimulation in the lateral preoptic area (LPA) leading to either relaxation or contraction of the bladder in cats.
- The study examined the effects of Angiotensin-(1-7) and its antagonist on intravesical pressure (IP) and cardiovascular functions in rats, finding that Ang-(1-7) increased IP without affecting blood pressure or heart rate.
- Gene and protein expressions of Mas receptors and ACE-2 were confirmed in the LPA, highlighting its crucial role in bladder control via Ang-(1-7) activation.
Epidermolysis bullosa describes a group of skin conditions caused by mutations in genes encoding proteins related to dermal-epidermal adhesion. In the United States, 50 cases of epidermolysis bullosa per 1 million live births are estimated, 92% of which classified as simplex, 5% dystrophic, 1% junctional and 2% non-classified. Dystrophic epidermolysis bullosa is associated with autosomal, dominant and recessive inheritance.
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