Nosocomial infections from carbapenem-resistant Klebsiella pneumoniae (CRKP) lead to high mortality rates, particularly in neurosurgery patients, with limited literature on CRKP-related meningitis.
This study reports two cases of CRKP meningitis following neurosurgery, highlighting multidrug-resistant strains identified using the Vitek Compact System and genetic typing revealing two novel clones (ST1298 and ST2687).
Treatment involved intrathecal polymyxin, and the authors recommend this approach for managing meningitis caused by multidrug-resistant K. pneumoniae.