Publications by authors named "Gustavo Anez"
Article Synopsis
- Some studies suggest that relying only on clinical values to assess remission in rheumatoid arthritis (RA) can overlook subclinical inflammation, prompting the need for imaging tools like ultrasound (US) to improve therapy decisions.
- A multicenter study was conducted with RA patients fulfilling specific criteria to compare treatment outcomes based on clinical evaluation versus ultrasound findings, with follow-ups at 12, 18, and 24 months.
- Results indicated that while both groups experienced disease exacerbations, most complications occurred in the clinical group, highlighting the potential benefit of integrating ultrasound assessments into treatment optimization for RA patients.
Rheumatoid arthritis (RA) prevalence is believed to be around 1% worldwide, although it varies considerably among different populations. The aim of EPISER2016 study was to estimate the prevalence of RA in the general adult population in Spain. We designed a population-based cross-sectional study.
View Article and Find Full Text PDFObjectives: To investigate the incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases receiving targeted biologic and synthetic disease modifying anti-rheumatic drugs (tDMARDs) and to explore the possible effect of these treatments in the clinical expression of COVID-19.
Methods: A cross-sectional study comprising of a telephone survey and electronic health records review was performed including all adult and paediatric patients with rheumatic diseases treated with tDMARDs in a large rheumatology tertiary centre in Barcelona, Spain. Demographics, disease activity, COVID-19 related symptoms and contact history data were obtained from the start of the 2020 pandemic.
Background/objective: Granulomatosis with polyangiitis (GPA) is a systemic necrotizing vasculitis that often results in frequent hospitalizations. We investigated the characteristics and predictors of 30-day hospital readmissions in GPA.
Methods: We performed a cross-sectional analysis using the 2014 National Readmission Database.
Systemic lupus erythematosus and rheumatoid arthritis are autoimmune diseases characterised by B-cell hyperactivation and production of autoantibodies (AutoAbs) against various self-antigens, including extractable nuclear antigens and citrullinated peptides. Therefore, B lymphocytes and antibody-secreting cells are considered relevant targets for therapies. However, isolation and characterisation of auto-reactive specific B lymphocytes are limited, primarily due to technical issues.
View Article and Find Full Text PDFDisturbances of plasma cell homeostasis and auto-antibody production are hallmarks of systemic lupus erythematosus. The aim of this study was to explore the presence of circulating anti-ENA and anti-dsDNA antibody-secreting cells, to determine their dependence on plasma cell-niche cytokines and to analyze their clinical value. The study was performed in SLE patients with serum anti-ENA and/or anti-dsDNA antibodies (n = 57).
View Article and Find Full Text PDF