Publications by authors named "Gustav Sindelka"
The aim of our study was to compare insulin sensitivity in lean and obese European polycystic ovary syndrome (PCOS) women with lean healthy women. We performed the euglycemic hyperinsulinemic clamp in 83 women with PCOS [53 lean with body mass index (BMI) of 21.5 +/- 1.
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- The study compared insulin sensitivity measured using hyperinsulinemic clamps against the HOMA and QUICKI indexes across different groups, including type 2 diabetics, insulinoma patients, and others.
- Results showed a strong correlation between body mass index and insulin sensitivity, indicating that higher body weight negatively affects insulin action for most participants.
- While HOMA and QUICKI indexes generally aligned with clamp measurements in healthy subjects and type 2 diabetics, they did not accurately reflect insulin sensitivity in patients with insulinoma or primary hyperaldosteronism.