Publications by authors named "Gustav Bredell"
Article Synopsis
- Mature astrocytes are activated after tissue damage and help form glial scars, but their ability to regenerate after injury is usually limited.* -
- In a study, researchers used imaging to observe astrocytes in mice following the targeted removal of certain astrocytes, finding that surrounding astrocytes showed great plasticity and could repopulate lesions effectively.* -
- A specific type of mature astrocyte, called reactive progenitor-like (REPL) astrocytes, not only multiply but also support the migration of new cells to fill in damaged areas, highlighting a potential therapeutic avenue for treating neurological diseases linked to glial issues.*
Despite recent progress of automatic medical image segmentation techniques, fully automatic results usually fail to meet clinically acceptable accuracy, thus typically require further refinement. To this end, we propose a novel Volumetric Memory Network, dubbed as VMN, to enable segmentation of 3D medical images in an interactive manner. Provided by user hints on an arbitrary slice, a 2D interaction network is firstly employed to produce an initial 2D segmentation for the chosen slice.
View Article and Find Full Text PDFAstrocytes establish extensive networks via gap junctions that allow each astrocyte to connect indirectly to the vasculature. However, the proportion of astrocytes directly associated with blood vessels is unknown. Here, we quantify structural contacts of cortical astrocytes with the vasculature in vivo.
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