FEATURES OF HIV/AIDS PHARMACOTHERAPY IN PREGNANT WOMEN.

The article under consideration describes the main ways to reduce the likelihood of transmission of infection from mother to fetus, emphasizes the features of therapy for women during pregnancy and proposes methods and approaches for treating this disease. The above data speak in favor of an integrated approach to the treatment and prevention of HIV infection. An important role is played by the earliest possible initiation of drug therapy.

[The sociodemographic portrait of a patient living with HIV and visiting AIDS centers in Russia].

Aim: To study the sociodemographic data of people living with HIV who visit AIDS centers.

Subjects And Methods: A multicenter open-label study was conducted, which included the retrospective model "A patient's portrait". Outpatient records and questionnaires were analyzed in 7,000 patients older than 18 years of age who had visited AIDS centers in 27 regions of Russia from 1 April to 31 July 2014 and signed their informed consent form to participate in the study.

EFFECT OF CARBAMAZEPINE ON THE ACTIVITY OF CYP3A4 ISOENZYME IN PATIENTS WITH ALCOHOL ADDICTION.

According to literature data, isoenzyme CYP3A4 of cytochrome P450 is involved in biotransformation of drugs.,At the same time, there is evidence that carbamazepine induces CYP3A4 activity. The purpose of the study was to evaluate the effect of carbamazepine on the CYP3A4 activity in patients with alcohol addiction.

[Linex forte in the prevention and treatment of gastrointestinal diseases].

The paper discusses the properties of Lactobacillus acidophilus (LA-5) and Bifidobacterium animals subsp. lactis (BB-12) that are active ingredients of linex forte, as well as the results of their experimental and clinical studies in gastroenterology. It states dosing recommendations for the drug to treat gastrointestinal tract diseases in adults and children.