Determination of Interlaminar Shear Properties of Fibre-Reinforced Composites under Biaxial Loading: A New Experimental Approach.

The complexity of biaxial tests and analysis of their results makes it difficult to study the interlaminar shear properties of fibre-reinforced composites, particularly under through-thickness compression, which occurs in thick-walled composite elements. The improvements in experimental methods to study the features of the nonlinear behaviour of composites under biaxial loading is now an important and relevant task in the development aircraft structural elements made of carbon fibre-reinforced polymers. This study aimed to develop a new experimental approach for the reliable determination of the interlaminar shear properties of laminates under through-thickness compression using a standard testing machine.

[New approaches to treatment for malignant tumors using perfusion technologies].

The paper summarizes and analyzes the results of complex treatment of patients with malignant tumors performed in the N.N.Petrov Research Institute of Oncology using perfusion technologies.

[Endovideosurgery (minimally invasive surgery) in treatment for malignant tumors of female genital organs: a 5-year experience of the clinic of the N.N.Petrov Research Institute of Oncology].

During the period of 2010-2015 laparoscopic surgery was performed in 1263 patients: 1113 with endometrial cancer (588 hysterectomies, 509 hysterectomies with pelvic lymphadenectomy, among them 16 with sentinel lymph node (SLN) mapping with Indocyanine green (ICG)); 86 with cervical cancer (80 nerve-sparing radical hysterectomies (NSRH), among them 15 with SLN mapping, 6 radical vaginal trachelectomies with endovideoassisted lymphadenectomy); 64 with ovarian malignancies. The average operating time in the group of hysterectomies was 101 minutes, in the group of hysterectomies with pelvic lymphadenectomy - 184 minutes, in the group of NSRH - 230 minutes. Average blood loss was less than 50 ml.

[Intraoperative intraperitoneal chemoperfusion treatment with cisplatin and dioxadet on a model of peritoneal carcinomatosis in ovarian cancer: safety and efficacy evaluation].

A comparative study of safety and efficacy of normothermic and hyperthermic intraperitoneal chemoperfusion (IPEC and HIPEC) with cisplatin and dioxadet was carried out in 143 female Wistar rats. Ovarian cancer was inoculated intraperitoneally (i.p.

[CHEMOPERFUSION TECHNOLOGIES IN TREATMENT FOR MALIGNANT TUMORS].

The data of literature on possibility of the use of perfusion technologies in combined treatment for malignant tumors of different sites are presented. Possible complications during hyperthermic chemoperfusion are discussed and the effectiveness of this method is analyzed.

[INDOCYANINE GREEN (ICG) IN THE DETECTION OF SENTINEL LYMPH NODES IN ENDOMETRIAL AND CERVIX CANCER].

We analyzed the international and our own experience of using different dyes in the identification of sentinel lymph nodes in oncogynecological practice. We evaluated the possibility of using indocyanine green (ICG) in the detection of sentinel lymph nodes in patients with endometrial and cervical cancer. The first results of the use of ICG at the Oncogynecology Department of the N.

[LAPAROSCOPIC SURGERY FOR ENDOMETRIAL CANCER IN PATIENTS OVER 70 YEARS OF AGE].

Surgery is the main method in treatment for endometrial cancer. The complexity of treatment of endometrial cancer patients in elderly age is a result of a large number of comorbidities and, as a consequence, the potential possibility of a large number of intra--and postoperative complications. The article presents the international data and the analysis of own results of a use of laparoscopy in surgical treatment of these patients.

[RESULTS OF LAPAROSCOPIC SURGERY FOR ENDOMETRIAL CANCER: EXPERIENCE OF THE N. N. PETROV RESEARCH INSTITUTE OF ONCOLOGY].

For the period from September 2010 to September 2014 there were operated 513 patients with endometrial cancer using laparoscopic installation the Karl Storz company. 304 patients (59.2%) underwent hysterectomy with appendages, 209 (40.

[Neoadjuvant chemoradiotherapy in the combined treatment of patients with stage IB2-III cervical cancer].

There are provided own observations on the use of cisplatin and capecitabine in schemes of combined treatment of patients with cervical cancer. Their efficiency as radiosensitizing agents is showed. There are discussed possible indications for the use of cisplatin and capecitabine in cervical cancer patients with metastatic lymph nodes.

[Effectiveness of platinum-based chemotherapy in ovarian cancer patients with BRCA1/2 mutations].

The purpose of this study was to examine the clinical significance of mutations in BRCA1/2 in the formation of response to neoadjuvant platinum-based chemotherapy for ovarian cancer (OC). All patients who had had neoadjuvant chemotherapy (NCT) in our Institute from January 2000 till January 2013 were tested for carrier of mutations in BRCA1/2. In accordance with the BRCA-status we formed two groups--a group with hereditary advanced OC and a group with non-hereditary advanced OC.

[Results of treatment for recurrent cancer of the uterine cervix].

The investigation involved 285 patients suffering from recurrences and distant metastases of uterine carcinoma cases of 24% of all (primary tumor). All recurrences generally occurred 12-20 months after the beginning of specialized therapy in 3.3-40%, with 78.

[Assessment of effectiveness of preoperative chemoradiotherapy in patients with T1B-2ABN0-1M0 cervical cancer].

The potential of preoperative radiochemotherapy in combined treatment of cervical carcinoma T1B-2ABN0-1M0 has been investigated. The use of cisplatin raised the feasibility of radical surgery from 69 to 87%, as compared with radiation alone, and increased 2-year overall and relapse-free survival to 92.6% and 89.

[Endoscopic bronchial care in patients with chronic bronchitis].

Endoscopic bronchial sanitation was made in 194 patients with an exacerbation of chronic bronchitis. Catarrhal and purulent endobronchitis was endoscopically diagnosed in 121 and 73 patients, respectively. For endoscopic sanitation, therapeutical lavage was used at fiber bronchoscopy.

[Use of antibiotics in chronic bronchitis].

Whether it is advisable to use tarivide, a wide-spectrum acting antibiotic, in 193 patients aged 23 to 50 years who had chronic catarrhal bronchitis. The experimental group included 43 and 57 patients with chronic nonobstructive and obstructive bronchitis, respectively. For comparison, a matched group receiving penicillin comprised 40 and 53 patients, respectively.

[Secondary immunodeficiency syndrome in patients with chronic bronchitis].

To identify secondary immunodeficiency, the author examined 510 patients with various types of chronic bronchitis (CB) and revealed that 82.5% of the examinees had secondary immunodeficiency syndrome which was characterized by immunological alterations: decreased T lymphocyte counts which was most common in patients with obstructive CB, differences in lymphocytic proliferation in response to PGA, which indicates reductions in the functional activity of T cells and in effector links of the immunity system, an increase in the blood levels of circulating immune complexes, imbalance in the ratio of Ig classes. The leading clinical manifestation of patients with secondary immunodeficiency was an infectious process: frequent, advanced or chronic infections.

[A system of comprehensive screening for tuberculosis and other chronic diseases of the respiratory organs in a rural area].

Pulmonary disease screening system, including fluorography, interview and external respiration function tests was used in 6 regions of this country. Out of 90,262 people examined, 23,360 persons were subjected to external respiration function test. As a result of the screening, the following conditions were detected: active tuberculosis in 0.