[Establishing the species belonging of fragments and particles of striated muscle tissue by total IgG using quantitative solid-phase enzyme-linked immunosorbent assay].

Objective: Improving the way to establish the species belonging of muscle tissue fragments and particles using the quantitative solid-phase enzyme-linked immunosorbent assay method.

Material And Methods: We studied human muscle tissue fragments and particles (sampled 2-4 weeks before) and also dried extracts from the blood of certain animals, such as dogs, birds, pigs, and cats. The samples were studied using quantitative enzyme immunoassay with the domestic kit «IgG-total-ELISA-HEMA».

Performance Enhancement of the Polarimetric Fibre Optical Current Sensor at JET Using Polarisation Optimisation.

To achieve optimal operation of the polarimetry-based FOCS, the light polarisation state at the input of the sensing fibre part must be close to a linear one. In the case of a FOCS deployed on a tokamak, the Joint European Torus (JET) in the present work, the long fibre optics link between the laser source and the sensing fibre modifies the polarisation in an unpredictable way, making it unclear which source polarisation state is to be set. A method for performing the necessary polarisation adjustment in a systematic way is proposed based on the FOCS analysis.

Experimental Model for the Study of Reparative Bone Regeneration in the Reconstruction of the Lower Jaw.

An experimental in vivo model has been developed on the rabbit mandible to study reparative regeneration of alveolar bone after intercortical split osteotomy and the role of the periosteum in the process of reparative osteogenesis. The peculiarity of this model is fixation of the periosteum over the reconstruction zone, which allows preserving the bone block displaced during surgery and leads to the formation of an organotypic structure of the regenerate with cortical and spongy bone.

Distributed Poloidal Magnetic Field Measurement in Tokamaks Using Polarization-Sensitive Reflectometric Fiber Optic Sensor.

Determination of the poloidal magnetic field distribution in tokamaks is of prime importance for the successful operation of tokamaks. In this paper, we propose a polarization-sensitive reflectometry-based optical fiber sensor for measuring the spatial distribution of the poloidal magnetic field in tokamaks. The measurement method exploits the Rayleigh backscattering and Faraday magneto-optic effect in optical fibers.

Neutronics Simulations for DEMO Diagnostics.

One of the main challenges in the development of a plasma diagnostic and control system for DEMO is the need to cope with unprecedented radiation levels in a tokamak during long operation periods. A list of diagnostics required for plasma control has been developed during the pre-conceptual design phase. Different approaches are proposed for the integration of these diagnostics in DEMO: in equatorial and upper ports, in the divertor cassette, on the inner and outer surfaces of the vacuum vessel and in diagnostic slim cassettes, a modular approach developed for diagnostics requiring access to the plasma from several poloidal positions.

Gamma-radiation enhancement of sensing properties of FBGs in a few-mode polymer CYTOP fiber.

We investigate the effect of γ-radiation on temperature (T) and relative humidity (RH) sensitivities of polymer perfluorinated fiber Bragg gratings (FBGs). To this aim, different γ-radiation doses (80, 120, 160, and 520 kGy) were applied to a set of FBGs. We show that irradiated FBGs demonstrate an RH sensitivity rise with the received dose: from 13.

Assessment of the Structural Vibration Effect on Plasma Current Measurement Using a Fiber Optic Current Sensor in ITER.

In this paper, we assess the effect of cryostat bridge vibrations on the plasma current measurement accuracy when using a fiber optic current sensor (FOCS) in ITER. The impact of vibrations on the light polarization state was first experimentally investigated using a miniaturized mock-up which represented a relevant part of the ITER FOCS structure. The set-up was then numerically simulated using the Jones matrix approach.

Precursor beat length and spun period measurement of a spun fiber using polarization optical frequency domain reflectometry.

In this Letter, a novel, to the best of our knowledge, nondestructive method for measuring the spun fiber parameters (precursor beat length and spun period) is presented both theoretically and experimentally. The proposed technique is based on analyzing the polarization optical frequency domain reflectometer traces. Experimental results are in agreement with the theoretical predictions.

Online Gamma Radiation Monitoring Using Few-Mode Polymer CYTOP Fiber Bragg Gratings.

We investigated the gamma radiation response of fiber Bragg gratings (FBGs) inscribed in a few-mode polymer optical fiber. The fiber had a graded-index CYTOP core of 20 µm and XYLEX overclad of 250 µm in diameter. Four FBGs were exposed to gamma radiation during four irradiation sessions at a 5.

Restoration of miR-648 overcomes 5-FU-resistance through targeting ET-1 in gastric cancer cells in-vitro.

Background: Endothelin-1 (ET-1) is a peptide overexpressed in gastric cancer (GC) and linked to carcinogenesis and resistance to chemotherapy. Applying microRNAs (miRNAs/miRs) to downregulate ET-1 and reverse resistance to commonly used chemotherapy drugs such as 5-fluorouracil (5-FU) is practical.

Methods: The current study sought to evaluate the miR-648 expression in GC and any plausibility of its replacement, either with or without the combination of chemo agents to downregulate ET-1 expression through interaction with its target gene.

Plasma current measurement in ITER with a polarization-OTDR: impact of fiber bending and twisting on the measurement accuracy.

Using a polarization-sensitive optical time domain reflectometer (OTDR), plasma current in the International Thermonuclear Experimental Reactor (ITER) can be measured by investigating the Faraday effect-induced polarization rotation in a spun fiber placed around the Vacuum Vessel. However, intrinsic birefringence and external effects like fiber bending and twisting generate unwanted polarization changes and decrease the measurement accuracy. In this paper, a simulation-based approach is developed, considering bending and twisting effects to assess the performance of the reflectometer in measuring plasma current at ITER.

Preoperative AI-Driven Fluorescence Diagnosis of Non-Melanoma Skin Cancer.

The diagnosis and treatment of non-melanoma skin cancer remain urgent problems. Histological examination of biopsy material-the gold standard of diagnosis-is an invasive procedure that requires a certain amount of time to perform. The ability to detect abnormal cells using fluorescence spectroscopy (FS) has been shown in many studies.

Strain specific motility patterns and surface adhesion of virulent and probiotic Escherichia coli.

Bacterial motility provides the ability for bacterial dissemination and surface exploration, apart from a choice between surface colonisation and further motion. In this study, we characterised the movement trajectories of pathogenic and probiotic Escherichia coli strains (ATCC43890 and M17, respectively) at the landing stage (i.e.

Photonic response and temperature evolution of SiO/TiO multilayers.

Unlabelled: The microstructural and optical reflectivity response of photonic SiO/TiO nanomultilayers have been investigated as a function of temperature and up to the material system's melting point. The nanomultilayers exhibit high, broadband reflectivities up to 1350 °C with values that exceed 75% for a 1 μm broad wavelength range (600-1600 nm). The optimized nanometer sized, dielectric multilayers undergo phase transformations from anatase TiO and amorphous SiO to the thermodynamically stable phases, rutile and cristobalite, respectively, that alter their structural morphology from the initial multilayers to that of a scatterer.

Cobalt and silver nanocoatings for reactor dosimetry.

Activation foils are an important tool for the characterization of neutron fields. Some of the materials that are used in these foils have large interaction cross-sections that cause unwanted self-shielding effects. In practice experimenters minimize these effects by using aluminium alloys.

Bacterial hepatocyte growth factor receptor agonist stimulates hepatocyte proliferation and accelerates liver regeneration in a partial hepatectomy rat model.

Hepatocyte growth factor (HGF) is central to liver regeneration. The Internalin B (InlB) protein is a virulence factor produced by the pathogenic bacterium Listeria monocytogenes. InlB is known to mimic HGF activity by interacting with the HGF receptor (HGFR) and activating HGFR-controlled signaling pathways.

An Model of Nonattached Biofilm-Like Bacterial Aggregates Based on Magnetic Levitation.

Chronic infections are associated with the formation of nonattached biofilm-like aggregates. models of surface-attached biofilms do not always accurately mimic these processes. Here, we tested a new approach to create nonattached bacterial aggregates using the principle of magnetic levitation of biological objects placed into a magnetic field gradient.

The response of water flow, suspended sediment yield and erosion intensity to contemporary long-term changes in climate and land use/cover in river basins of the Middle Volga Region, European Russia.

The Middle Volga Region is one of the most populated and agriculturally developed geographic regions of the East European Plain within European Russia, where noticeable changes in climate and land use/cover were observed since the 1980s and the early 1990s respectively. The long-term year-to-year (trend) variability (during mainly 1960-2016) in water flow and suspended sediment yield of 14 small and medium-size rivers in the Middle Volga Region was analyzed in the paper. It is shown that in all the studied rivers there was a statistically significant decrease (on average, by 77.

Possibilities of Manufacturing Products from Cermet Compositions Using Nanoscale Powders by Additive Manufacturing Methods.

Complicated wear-resistant parts made by selective laser melting (SLM) of powder material based on compositions of metal and ceramics can be widely used in mining, oil engineering, and other precision engineering industries. Ceramic-metal compositions were made using nanoscale powders by powder metallurgy methods. Optimal regimes were found for the SLM method.

CYTOP Fibre Bragg Grating Sensors for Harsh Radiation Environments.

We present a polymer fibre Bragg grating sensor and its sensitivity to gamma radiation by observing the reflected spectral profile. The Bragg grating is femtosecond inscribed within a perfluorinated CYTOP fibre and the alteration of the Bragg wavelength corresponds to the total radiation dose received. Over a total dose of 41 k Gy, the fibre demonstrates a sensitivity of - 26.

The impact of contemporary changes in climate and land use/cover on tendencies in water flow, suspended sediment yield and erosion intensity in the northeastern part of the Don River basin, SW European Russia.

The basin of the Don River (the fifth longest river in Europe), located mainly in the forest-steppe and steppe landscape zones, is one of the most populated and agriculturally developed regions of the East European (Russian) Plain. Sheet, rill and gully erosion occurring chiefly in snowmelt period (March-April) and also in moderate-to-heavy-rainfalls season (chiefly May-to-September) is the main factor of present-day soil degradation within cultivated lands of this basin. Using monitoring hydrological data, it is shown, by the examples of the Khopyor River and the Medveditsa River flowing in the northeastern part of the Don River basin (SW European Russia), that suspended sediment yield of the rivers, as an objective and sufficiently accurate indicator of total erosion intensity in river basins, was reduced by 3.

Theoretical assessment of the OTDR detector noise on plasma current measurement in tokamaks.

In this paper, we propose a theoretical study dedicated to the assessment of plasma current measurement in magnetic confinement fusion reactors using a polarization optical time-domain reflectometer (POTDR) setup with a low-birefringence fiber used as the sensing fiber. We consider the general case of a non-uniform magnetic-field distribution along the sensing fiber. The numerical simulations, based on Jones formalism taking into account the OTDR noise, provide the measurement error as a function of the plasma current.

[The conditions and the character of the work of the mortuary personnel in the Great Britain: the problems of health protection, anti-infectious prophylaxis, and reduction of the risk of contamination].

The objective of the present work was to study the specific approaches to the organization of the work of the foreign specialists performing post-mortem autopsies of the subjects who died from infectious pathology and consider the proposals of the representatives of the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) concerning accreditation of mortuaries in the Great Britain. It is shown that the algorithm for the evaluation of the possible risks of contamination of the medical personnel suggests the solution of five problems that envisages obtaining the answers to the following questions: (1) what biological agents can be present in a particular case? (2) what is their virulence factor? (3) what are the transmission routes (mechanisms)? (4) what are the manner of their realization? (5) what is the amount of the pathogen(s) needed to cause a given infectious disease? The anti-infectious prophylactic measures and the prevention of the contamination risks for the medical personnel of the British mortuaries are designed to safeguard the people against the infection with the causative agents of tuberculosis, viral hepatitis B and C, HIV, and Kreutsfield- Jacob's disease. All the employees engaged in the pathological studies must wear specialized clothing in a mandatory manner and make use of the equipment for the personal and collective protection.

[The diagnostic criteria for the improper care of the elderly subjects and their forensic medical significance].

The demographic ageing of the population is accompanied by the gradual increase in the number of the people of the advanced age both in Russia and in other countries all over the world. This situation enhances the probability of violence and the improper care of the elderly subjects both in their families and in the specialized socio-medical facilities. The objective of the present work was to study the experience of the foreign specialists dealing with the problem of the improper care for the elderly subjects with a view to the identification of the diagnostic criteria for the application in the forensic medical practice.