Development and validation of an international risk prediction algorithm for episodes of major depression in general practice attendees: the PredictD study.

Context: Strategies for prevention of depression are hindered by lack of evidence about the combined predictive effect of known risk factors.

Objectives: To develop a risk algorithm for onset of major depression.

Design: Cohort of adult general practice attendees followed up at 6 and 12 months.

Relative risk of diabetes, dyslipidaemia, hypertension and the metabolic syndrome in people with severe mental illnesses: systematic review and metaanalysis.

Background: Severe mental illnesses (SMI) may be independently associated with cardiovascular risk factors and the metabolic syndrome. We aimed to systematically assess studies that compared diabetes, dyslipidaemia, hypertension and metabolic syndrome in people with and without SMI.

Methods: We systematically searched MEDLINE, EMBASE, CINAHL & PsycINFO.

Prevalence of common mental disorders in general practice attendees across Europe.

Background: There is evidence that the prevalence of common mental disorders varies across Europe.

Aims: To compare prevalence of common mental disorders in general practice attendees in six European countries.

Method: Unselected attendees to general practices in the UK, Spain, Portugal, Slovenia, Estonia and The Netherlands were assessed for major depression, panic syndrome and other anxiety syndrome.

Relative risk of cardiovascular and cancer mortality in people with severe mental illness from the United Kingdom's General Practice Rsearch Database.

Context: People with severe mental illness (SMI) appear to have an elevated risk of death from cardiovascular disease, but results regarding cancer mortality are conflicting.

Objective: To estimate this excess mortality and the contribution of antipsychotic medication, smoking, and social deprivation.

Design: Retrospective cohort study.

Harmful alcohol use in Goa, India, and its associations with violence: a study in primary care.

Aims: To determine (i) the prevalence and characteristics of harmful alcohol consumption in general practice attendees; (ii) social and psychological associations with harmful drinking and (iii) recognition of harmful drinking by GPs.

Methods: A cross-sectional study of ten general practices in Goa, India. A total of 1567 general practice attendees were recruited.