[Characteristics of morphological and functional liver disorders in mechanical jaundice under clinical and experimental conditions].

Clinical and morphological studies on 19 cases of cholelithiasis complicated with mechanical jaundice have been carried out together with experiments on 36 white mongrel rats, in which mechanical jaundice was modelled. The recovery of liver morphology takes a long time. After the recovery of the biliary tract patency liver changes subside very slowly, and within 60 days dystrophic processes in the liver parenchyma get evident.

[Not Available].

Considering the accumulation of many facts, actually, in all branches of science the lack is felt of extensive and fundamental generalizations, of theories which would be in a position to explain these facts. The same holds true for medicine, where, periodically discussions are resumed on various theories of diseases and on the general theory of pathology. Pathology is determined by four elements: accumulation of experimental data, specific research ethods, hypotheses and theories and philosophical basis of the pathological theory--its methodological principles.