Evaluation of apically extruded debris following glide-path preparation with different file systems.

The amount of apically extruded debris following glide-path preparation of mesial root of 120 freshly extracted human mandibular molar teeth using Senseus ProFinder files, PathFile, G-Files, Scout-RaCe files, HyFlex glidepath files and V glide-path two file system is of interest. The Eppendorf tubes were used as test equipment for collecting debris and the average weight of the debris was measured using an electronic micro-balancing system. It was observed that regardless of the file system utilized, debris was expelled from the apex.

Reductions in Insulin Resistance are Mediated Primarily via Weight Loss in Subjects With Type 2 Diabetes on Semaglutide.

Context: Semaglutide, a once-weekly glucagon-like peptide-1 analog approved for use in patients with type 2 diabetes (T2D), demonstrated superior body weight (BW) reductions and decreased insulin resistance (IR) vs comparators across the Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN) 1-3 clinical trials.

Objective: To investigate the relationship between IR and BW across the SUSTAIN 1-3 trials.

Design: Post hoc analysis of the SUSTAIN 1-3 trials.

GREATER COMBINED REDUCTIONS IN HbA ≥1.0% AND WEIGHT ≥5.0% WITH SEMAGLUTIDE VERSUS COMPARATORS IN TYPE 2 DIABETES.

Semaglutide is a glucagon-like peptide 1 (GLP-1) analog for the once-weekly treatment of type 2 diabetes (T2D). In the global SUSTAIN clinical trial program, semaglutide demonstrated superior glycated hemoglobin (HbA) and body weight reductions versus comparators. This post hoc analysis compared the proportion of patients achieving combined reductions in glycemia and body weight versus comparators.

Semaglutide as a therapeutic option for elderly patients with type 2 diabetes: Pooled analysis of the SUSTAIN 1-5 trials.

The efficacy and safety of semaglutide vs comparators in non-elderly (<65 years) and elderly (≥65 years) patients with type 2 diabetes (T2D) across the SUSTAIN 1-5 trials were evaluated. Patients were randomized to once-weekly subcutaneous semaglutide (0.5 or 1.

Radix mesiolingualis and radix distolingualis: a case report of a tooth with an unusual morphology.

Variation in the root and canal morphology of the maxillary first molars is quite common. The most common configuration is 3 roots and 3 or 4 canals. Nonetheless, other possibilities still exist.

Endodontic management of a maxillary first molar with three roots and seven root canals with the aid of cone-beam computed tomography.

Variation in root canal morphology, especially in maxillary first molar presents a constant challenge for a clinician in their detection and management. This case report describes the successful root canal treatment of a three rooted right maxillary first molar presenting with three canals each in the mesiobuccal and distobuccal roots and one canal in the palatal root. The clinical detection of this morphologic aberration was made using a dental operating microscope, and the canal configuration was established after correlating and computing the clinical, radiographic and cone-beam computed tomography (CBCT) scan findings.

Evaluation of apical extrusion of debris and irrigant using two new reciprocating and one continuous rotation single file systems.

Objective: Apical extrusion of debris and irrigants during cleaning and shaping of the root canal is one of the main causes of periapical inflammation and postoperative flare-ups. The purpose of this study was to quantitatively measure the amount of debris and irrigants extruded apically in single rooted canals using two reciprocating and one rotary single file nickel-titanium instrumentation systems.

Materials And Methods: Sixty human mandibular premolars, randomly assigned to three groups (n = 20) were instrumented using two reciprocating (Reciproc and Wave One) and one rotary (One Shape) single-file nickel-titanium systems.

Endodontic management of an unusual maxillary first molar with a single buccal root.

Aim: The aim of this clinical article is to describe the unusual anatomy that was detected in a maxillary first molar during routine endodontic treatment.

Background: Variation in Root and Root canal morphology especially in multirooted teeth presents a constant challenge for a clinician in their detection and management. The literature is replete with cases that have extra canal or Root but cases with fused Root and fewer numbers of canals are sparse.

Biodentine-a novel dentinal substitute for single visit apexification.

Use of an apical plug in management of cases with open apices has gained popularity in recent years. Biodentine, a new calcium silicate-based material has recently been introduced as a dentine substitute, whenever original dentine is damaged. This case report describes single visit apexification in a maxillary central incisor with necrotic pulp and open apex using Biodentine as an apical barrier, and a synthetic collagen material as an internal matrix.

Asymmetry in mesial root number and morphology in mandibular second molars: a case report.

Ambiguity in the root morphology of the mandibular second molars is quite common. The most common root canal configuration is 2 roots and 3 canals, nonetheless other possibilities may still exist. The presence of accessory roots is an interesting example of anatomic root variation.

A variation in tooth position-180° rotated maxillary second premolar.

Rotation of a tooth around an axis which is perpendicular to the occlusal plane through angles which approach 180° is a rare anomaly which is found in the human dentition. Such aberrations present a multi-factorial model in their origin. Both genetic and local factors seem to contribute to this abnormality.

Using spiral computed tomography for endodontic management of a mandibular first molar with a middle mesial canal: a case report.

The root canal anatomy of a permanent mandibular first molar has been traditionally described as 2 roots--1 mesial and 1 distal--with 2 canals in the mesial root and 1 or 2 canals in the distal root. Nonetheless, other possibilities exist. The presence of a third canal in the mesial root has been reported to have an incidence of 0%-17%.

Paramolar - A supernumerary molar: A case report and an overview.

Paramolar is a supernumerary molar usually small and rudimentary, most commonly situated buccally or palatally to one of the maxillary molars. Paramolar is a developmental anomaly and has been argued to arise from a combination of genetic and environmental factors. Reports of this entity are rarely found in the dental literature.

Paramolar tubercle: A diversity in canal configuration identified with the aid of spiral computed tomography.

The objective of this article is to increase our understanding of the root canal system of the anomalous structures like paramolar tubercles. The knowledge of the internal anatomy of the paramolar tubercles is very important as they influence the treatment modalities and associated problems in many dental disciplines. This case report investigates the anatomical and morphological characteristics of a rare case of two well-developed lobulated cusps occurring on the buccal surface of maxillary right second molar with the aid of spiral computed tomography.