Background: To interpret 51Cr-EDTA measurements of glomerular filtration rate (GFR) it is usual to correct results for a patient's body size by scaling values to a standard body surface area (BSA) of 1.73 m(2).
Aim: To use 51Cr-EDTA data for a large group of healthy subjects to derive the optimum mathematical function for the body size correction that minimized the variance of the corrected GFR values.
Background And Aim: 51Cr-Ethylenediaminetetraacetic acid (51Cr-EDTA) is widely used to measure the glomerular filtration rate (GFR) for the assessment of renal function. The aims of this study were to assess the dependence of GFR on age and gender and to produce reference data for the interpretation of 51Cr-EDTA GFR measurements in adults.
Methods: This was a retrospective study of 428 subjects (218 females, 210 males; age range, 19-72 years) undergoing assessment as live kidney donors.