Bloody neonatal diaper.

As part of the ongoing effort to minimize health care expenses, mothers and newborns are being discharged after shorter hospital stays. Problems that previously would have been noticed in the hospital nursery are now being seen in the emergency department. We report the case of a 1-day-old infant who was brought to our ED with grossly bloody stool.

Acidic and basic fibroblast growth factors delay the maturation of neural crest-derived neurons.

Neural crest (NC) cultures were prepared from lumbosacral segments of 12 day rat embryos and maintained in a defined medium. Post-mitotic, flat, neurofilament+ neurons with broad neuritic processes ('nascent neurons') appeared within 24 h. Timing of the next stage in neuronal differentiation, the formation of bipolar, phase-bright cells that bound tetanus toxin with long, slender neurites ('bipolar neurons'), was markedly influenced by acidic or basic fibroblast growth factor (FGF).