Mechanical properties of bioactive glasses, ceramics, glass-ceramics and composites: State-of-the-art review and future challenges.

The repair and restoration of bone defects in orthopaedic and dental surgery remains a major challenge despite advances in surgical procedures and post-operative treatments. Bioactive glasses, ceramics, glass-ceramics and composites show considerable potential for such applications as they can promote bone tissue regeneration. This paper presents an overview of the mechanical properties of various bioactive materials, which have the potential for bone regeneration.

Influence of CuO/MgO ratio on the gene expression, cytocompatibilty, and antibacterial/anticancerous/analgesic drug loading kinetics for (15-x) CuO-xMgO-10P O -60SiO -10CaO-5ZnO (2.5 ≤ x ≤ 12.5) mesoporous bioactive glasses.

In the present study, novel mesoporous bioactive glasses (MBGs) (15-x)CuO-xMgO-10P O -60SiO -10CaO-5ZnO (2.5 ≤ x ≤ 12.5, varying in steps of 2) are synthesized using the sol-gel technique.

Effect of copper on the up-regulation/down-regulation of genes, cytotoxicity and ion dissolution for mesoporous bioactive glasses.

In the present study, copper-based (25 - x)CaO - xCuO -10PO - 5BO - 60SiO (x = 2.5, 5, 7.5, 10 mol%) mesoporous bioactive glasses (MBGs) were synthesized using the sol-gel technique with cetyltrimethyl ammonium bromide as the structure-directing agent.

Effect of strontium substitution on the cytocompatibility and 3-D scaffold structure for the xSrO-(10-x) MgO-60SiO-20CaO-10 PO (2 ≤ x ≤ 8) sol-gel glasses.

In the present study, novel glasses xSrO-(10-x) MgO-60SiO-20CaO-10 PO (2 ≤ x ≤ 8, in steps of 2) are synthesized via sol-gel method. The current work focusses on the evaluation of mechanical, physical and biocompatible properties for sol-gel glasses. The pore size and surface area of these glasses were studied using BET analysis.

Antibacterial and anticancerous drug loading kinetics for (10-x)CuO-xZnO-20CaO-60SiO-10PO (2 ≤ x ≤ 8) mesoporous bioactive glasses.

In the present study, antibacterial and anticancerous drug loading kinetics for the (10-x)CuO-xZnO-20CaO-60SiO-10PO (2≤x≤8, varying in steps of 2) mesoporous bioactive glasses (MBGs) have been studied. XRD analysis of the as prepared glass samples proved its amorphous nature. Scanning electron microscopy (SEM) revealed the apatite layer formation on the surface of the MBGs after soaking for 15 days in SBF.

Review and the state of the art: Sol-gel and melt quenched bioactive glasses for tissue engineering.

Biomaterial development is currently the most active research area in the field of biomedical engineering. The bioglasses possess immense potential for being the ideal biomaterials due to their high adaptiveness to the biological environment as well as tunable properties. Bioglasses like 45S5 has shown great clinical success over the past 10 years.

Synthesis, cytotoxicity, and hydroxyapatite formation in 27-Tris-SBF for sol-gel based CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses.

CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses were prepared via an optimized sol-gel method. The current investigation was focused on producing novel zinc based calcium phosphoborosilicate glasses and to evaluate their mechanical, rheological, and biocompatible properties. The morphology and composition of these glasses were studied using X-ray diffraction (XRD) and scanning electron microscopy (SEM).

A review of bioactive glasses: Their structure, properties, fabrication and apatite formation.

Bioactive glass and glass-ceramics are used in bone repair applications and are being developed for tissue engineering applications. Bioactive glasses/Bioglass are very attractive materials for producing scaffolds devoted to bone regeneration due to their versatile properties, which can be properly designed depending on their composition. An important feature of bioactive glasses, which enables them to work for applications in bone tissue engineering, is their ability to enhance revascularization, osteoblast adhesion, enzyme activity and differentiation of mesenchymal stem cells as well as osteoprogenitor cells.

Assessment of in vitro bioactivity of SiO-BaO-ZnO-BO-AlO glasses: An optico-analytical approach.

Bioactive glasses are an important subclass of biomaterials. The bioactivity of a glass depends on its initial constituents and their respective amounts. In the present investigation, five barium-zinc-borosilicate glass samples have been studied by varying AlO mol% to check their bioactivity.